# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4712219 | B | Protac activity at CRBN/MEK1 in human HT-29 cells assessed as induction of MEK1 degradation at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
2. | ALA4712220 | B | Protac activity at CRBN/MEK2 in human HT-29 cells assessed as induction of MEK1 degradation at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
3. | ALA4712232 | B | Protac activity at CRBN/MEK1 in human SK-MEL-28 cells assessed as induction of MEK1 degradation at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4712233 | B | Protac activity at CRBN/MEK2 in human SK-MEL-28 cells assessed as induction of MEK2 degradation at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4712236 | B | Inhibition of ERK phosphorylation in human HT-29 cells at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA4712237 | B | Inhibition of MEK2 phosphorylation in human HT-29 cells at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA4712238 | B | Inhibition of MEK1 phosphorylation in human HT-29 cells at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA4712270 | B | Binding affinity to MEK1 (unknown origin) incubated for 1 hr by qPCR based KINOMEscan assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
9. | ALA4712271 | B | Binding affinity to MEK2 (unknown origin) incubated for 1 hr by qPCR based KINOMEscan assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
10. | ALA4712273 | F | Effect on global proteome expression in human HT-29 cells at 0.3 uM incubated for 8 hrs by mass spectrometry analysis based global proteome analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4712280 | F | Antiproliferative activity against human SK-MEL-28 cells incubated for 3 days by WST8 assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
12. | ALA4712282 | F | Inhibition of colony formation in human HT-29 cells at 30 to 300 nM incubated for 10 days by crystal violet staining based assay | Homo sapiens | 2 | cell-based format | Scientific Literature |