| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4771535 | B | Inhibition of wild type EGFR in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell viability assay | Mus musculus | 15 | ALA4765363 | cell-based format | Scientific Literature | |
| 2. | ALA4771536 | B | Inhibition of TEL-fused EGFR (unknown origin) transfected in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 15 | ALA4765363 | cell-based format | Scientific Literature | |
| 3. | ALA4771537 | B | Inhibition of TEL-fused EGFR L858R mutant (unknown origin) transfected in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 15 | ALA4765363 | cell-based format | Scientific Literature | |
| 4. | ALA4771538 | B | Inhibition of TEL-fused EGFR T790M/L858R mutant (unknown origin) transfected in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 15 | ALA4765363 | cell-based format | Scientific Literature | |
| 5. | ALA4771539 | B | Inhibition of TEL-fused EGFR C797S mutant (unknown origin) transfected in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 1 | ALA4765363 | cell-based format | Scientific Literature | |
| 6. | ALA4771540 | B | Inhibition of wild type EGFR in human A549 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 14 | ALA4765363 | cell-based format | Scientific Literature | |
| 7. | ALA4771541 | B | Inhibition of EGFR L858R mutant in human NCI-H3255 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 15 | ALA4765363 | cell-based format | Scientific Literature | |
| 8. | ALA4771543 | B | Inhibition of EGFR L858R mutant in human NCI-H3255 cells assessed as cell growth inhibition measured after 72 hrs in presence of ZnCl2 by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 1 | ALA4765363 | cell-based format | Scientific Literature | |
| 9. | ALA4771544 | B | Inhibition of wild type EGFR in human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4765363 | cell-based format | Scientific Literature | |
| 10. | ALA4771545 | B | Inhibition of wild type EGFR in human MCF7 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4765363 | cell-based format | Scientific Literature | |
| 11. | ALA4771546 | B | Inhibition of wild type EGFR in human HT-29 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4765363 | cell-based format | Scientific Literature | |
| 12. | ALA4771547 | B | Inhibition of wild type EGFR in human A-431 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4765363 | cell-based format | Scientific Literature | |
| 13. | ALA4771548 | A | Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 72 hrs by Celltiter-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4765363 | cell-based format | Scientific Literature | |
| 14. | ALA4771549 | B | Inhibition of EGFR L858R mutant phosphorylation at Y1068 residue in human NCI-H3255 cells measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4765363 | cell-based format | Scientific Literature | |
| 15. | ALA4771550 | F | Cell cycle arrest in human NCI-H3255 cells assessed as accumulation at G0/G1 phase at 1 uM measured after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 53.55%) | Homo sapiens | 1 | ALA4765363 | cell-based format | Scientific Literature | |
| 16. | ALA4771551 | F | Cell cycle arrest in human NCI-H3255 cells assessed as accumulation at S phase at 1 uM measured after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 36.26%) | Homo sapiens | 1 | ALA4765363 | cell-based format | Scientific Literature | |
| 17. | ALA4771552 | F | Cell cycle arrest in human NCI-H3255 cells assessed as accumulation at G2/M phase at 1 uM measured after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 10.18%) | Homo sapiens | 1 | ALA4765363 | cell-based format | Scientific Literature | |
| 18. | ALA4771553 | F | Cell cycle arrest in human NCI-H3255 cells assessed as accumulation at G0/G1 phase at 5 uM measured after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 53.55%) | Homo sapiens | 1 | ALA4765363 | cell-based format | Scientific Literature | |
| 19. | ALA4771554 | F | Cell cycle arrest in human NCI-H3255 cells assessed as accumulation at S phase at 5 uM measured after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 36.26%) | Homo sapiens | 1 | ALA4765363 | cell-based format | Scientific Literature | |
| 20. | ALA4771555 | F | Cell cycle arrest in human NCI-H3255 cells assessed as accumulation at G2/M phase at 5 uM measured after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 10.18%) | Homo sapiens | 1 | ALA4765363 | cell-based format | Scientific Literature |
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