# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4718936 | F | Agonist activity at Go2-q-coupled human EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 1 hr by scintillation counting analysis | Homo sapiens | 3 | ALA4715765 | cell membrane format | Scientific Literature | |
2. | ALA4718937 | B | Agonist activity at Go2-q-coupled rat EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 1 hr by scintillation counting analysis | Rattus norvegicus | 3 | ALA4715765 | cell membrane format | Scientific Literature | |
3. | ALA4718938 | F | Agonist activity at Go2-q-coupled mouse EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 1 hr by scintillation counting analysis | Mus musculus | 3 | ALA4715765 | cell membrane format | Scientific Literature | |
4. | ALA4718939 | F | Agonist activity at Go2-q-coupled human EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding at 1 uM preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 1 hr by scintillation counting analysis relative to control | Homo sapiens | 3 | ALA4715765 | cell membrane format | Scientific Literature | |
5. | ALA4718940 | B | Agonist activity at Go2-q-coupled rat EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding at 1 uM preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 1 hr by scintillation counting analysis relative to control | Rattus norvegicus | 3 | ALA4715765 | cell membrane format | Scientific Literature | |
6. | ALA4718941 | F | Agonist activity at Go2-q-coupled mouse EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding at 1 uM preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 1 hr by scintillation counting analysis relative to control | Mus musculus | 3 | ALA4715765 | cell membrane format | Scientific Literature | |
7. | ALA4718942 | A | Metabolic stability in mouse liver microsomes assessed as half life | Mus musculus | 2 | ALA4715765 | microsome format | Scientific Literature | |
8. | ALA4718943 | A | Metabolic stability in rat liver microsomes assessed as half life | Rattus norvegicus | 2 | ALA4715765 | microsome format | Scientific Literature | |
9. | ALA4718944 | A | Metabolic stability in human liver microsomes assessed as half life | Homo sapiens | 2 | ALA4715765 | microsome format | Scientific Literature | |
10. | ALA4718951 | A | Elimination half-life in po dosed mouse | Mus musculus | 1 | ALA4715765 | organism-based format | Scientific Literature |