# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4685760 | B | Protac activity at VHL/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation measured after 16 hrs by immunoblotting analysis | Homo sapiens | 3 | ALA4680217 | cell-based format | Scientific Literature | |
2. | ALA4685762 | F | Antiproliferative activity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 56 | ALA4680217 | cell-based format | Scientific Literature | |
3. | ALA4685763 | B | Protac activity at VHL/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation by measuring remaining BCL-XL level at 100 nM measured after 16 hrs by immunoblotting analysis relative to control | Homo sapiens | 25 | ALA4680217 | cell-based format | Scientific Literature | |
4. | ALA4685764 | B | Protac activity at VHL/BCL2 in human MOLT-4 cells assessed as induction of BCL2 degradation at 100 nM measured after 16 hrs by immunoblotting analysis | Homo sapiens | 25 | ALA4680217 | cell-based format | Scientific Literature | |
5. | ALA4685768 | F | Antiproliferative activity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 8 | ALA4680217 | cell-based format | Scientific Literature | |
6. | ALA4685769 | F | Antiproliferative activity against human NCI-H146 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 8 | ALA4680217 | cell-based format | Scientific Literature | |
7. | ALA4685770 | T | Toxicity in human platelet assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 8 | ALA4680217 | tissue-based format | Scientific Literature | |
8. | ALA4685771 | U | Selectivity index, ratio of IC50 for human platelet to IC50 for human MOLT-4 cells | Homo sapiens | 8 | ALA4680217 | assay format | Scientific Literature |