| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4676829 | T | Acute toxicity in po dosed dog administered as repeated dose for 28 days | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA4676830 | T | Acute toxicity in po dosed dog administered as single dose for 28 days | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA4676831 | T | Acute toxicity in po dosed mouse administered as repeated dose for 28 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA4676832 | T | Acute toxicity in po dosed mouse administered as single dose for 28 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4676833 | F | Memory enhancing effect in Sprague-Dawley rat model of ibotenic-acid-induced impairment of forebrain cholinergic projection system assessed as improvement in reference memory at 0.36 to 1.4 micromol/kg, po by radial arm maze test relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA4676834 | F | Memory enhancing effect in rat model of mecamylamine-induced amnesia assessed as decrease in latency to find platform at 0.3 to 3 micromol/kg, po by water-navigation test relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4676835 | F | Cognitive enhancing effect in Wistar rat assessed as reversal of scopolamine-induced amnesia at 0.6 micromol/kg, sc by passive-avoidance test relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4676836 | B | Agonist activity at rat alpha4beta2 expressed in Xenopus oocytes assessed as peak activation at 100 uM relative to control | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4676837 | F | In vivo agonist activity at nAChR in rat assessed as serotonin level in cortex at 3.6 micromol/kg, sc by microdialysis relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4676838 | F | In vivo agonist activity at nAChR in rat assessed as nor-epinephrine level in cortex at 3.6 micromol/kg, sc by microdialysis relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4676839 | F | In vivo agonist activity at nAChR in rat assessed as dopamine level in cortex at 3.6 micromol/kg, sc by microdialysis relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4676840 | F | In vivo agonist activity at nAChR in rat assessed as acetylcholine level in cortex at 3.6 micromol/kg, sc by microdialysis relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4676841 | B | Agonist activity at nAChR in rat striatal synaptosomes assessed as [3H]dopamine release relative to tetramethylammonium | Rattus norvegicus | 3 | subcellular format | Scientific Literature | ||
| 14. | ALA4676842 | B | Agonist activity at nAChR in rat striatal synaptosomes assessed as [3H]dopamine release | Rattus norvegicus | 3 | subcellular format | Scientific Literature | ||
| 15. | ALA4676843 | B | Agonist activity at alpha4beta2 nAChR in rat thalamic synaptosomes assessed as 86Rb efflux relative to tetramethylammonium | Rattus norvegicus | 2 | subcellular format | Scientific Literature | ||
| 16. | ALA4676844 | B | Agonist activity at alpha4beta2 nAChR in rat thalamic synaptosomes assessed as increase in 86Rb efflux | Rattus norvegicus | 2 | subcellular format | Scientific Literature | ||
| 17. | ALA4676859 | B | Inhbition of [3H] nicotine binding to rat brain alpha4beta2 nAChR | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 18. | ALA4676884 | B | Displacement of [3H]nicotine from sodium channel site2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4676885 | B | Displacement of [3H]nicotine from 5-hydroxytryptamine receptor 3A (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4676886 | B | Displacement of [3H]nicotine from 5-hydroxytryptamine receptor 2A (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |
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