# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4670872 | Binding | Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability | Homo sapiens | 48 | ALA4665807 | cell-based format | Scientific Literature | |
2. | ALA4670873 | Binding | Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1 | Homo sapiens | 48 | ALA4665807 | cell-based format | Scientific Literature | |
3. | ALA4670874 | Binding | Selectivity ratio of EC50 for Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1 to EC50 for Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability | Homo sapiens | 16 | ALA4665807 | cell-based format | Scientific Literature | |
4. | ALA5142938 | Functional | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis | Homo sapiens | 51 | ALA5137109 | cell-based format | Scientific Literature | |
5. | ALA5142939 | Functional | Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis | Homo sapiens | 56 | ALA5137109 | cell-based format | Scientific Literature | |
6. | ALA5142964 | Functional | Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days in presence of ferroptosis inhibitor, liproxstatin-1 by methylene blue staining based analysis | Homo sapiens | 4 | ALA5137109 | cell-based format | Scientific Literature | |
7. | ALA5142965 | Functional | Ratio of IC50 for cytotoxicity against human NCI-H522 cells in presence of ferroptosis inhibitor, liproxstatin-1 to IC50 for cytotoxicity against human NCI-H522 cells | Homo sapiens | 4 | ALA5137109 | cell-based format | Scientific Literature | |
8. | ALA5142966 | Functional | Cytotoxicity against human HT-1080 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis | Homo sapiens | 4 | ALA5137109 | cell-based format | Scientific Literature | |
9. | ALA5142967 | Functional | Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis | Homo sapiens | 4 | ALA5137109 | cell-based format | Scientific Literature | |
10. | ALA5142968 | Functional | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis | Homo sapiens | 4 | ALA5137109 | cell-based format | Scientific Literature | |
11. | ALA5142969 | Functional | Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis | Homo sapiens | 4 | ALA5137109 | cell-based format | Scientific Literature | |
12. | ALA5142970 | Functional | Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis | Homo sapiens | 4 | ALA5137109 | cell-based format | Scientific Literature | |
13. | ALA5142971 | Toxicity | Cytotoxicity against human WI-38 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis | Homo sapiens | 4 | ALA5137109 | cell-based format | Scientific Literature | |
14. | ALA5142972 | Toxicity | Cytotoxicity against mouse MEF cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis | Mus musculus | 4 | ALA5137109 | cell-based format | Scientific Literature |