# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4742447 | Binding | Inhibition of CDK8 in human SW-620 cells assessed as reduction in IFNgamma-induced STAT1 S727 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis | Homo sapiens | 8 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
2. | ALA4742448 | Binding | Inhibition of haspin in synchronized human SW620 cells assessed as reduction in IFNgamma-induced H3T3 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis | Homo sapiens | 8 | ALA4742387 | tissue-based format | Patent Bioactivity Data | |
3. | ALA4742449 | Binding | Inhibition of CDK8 in human SW-620 cells assessed as reduction in STAT1 S727 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis | Homo sapiens | 14 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
4. | ALA4742450 | Binding | Inhibition of haspin in human SW620 cells assessed as reduction in IFNgamma-induced H3T3 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis | Homo sapiens | 9 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
5. | ALA4742451 | Functional | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 24 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
6. | ALA4742452 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 24 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
7. | ALA4742453 | Functional | Antiproliferative activity against human SW-620 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 27 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
8. | ALA4742454 | Functional | Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 22 | ALA4742387 | cell-based format | Patent Bioactivity Data |