| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4734716 | F | Induction of cell cycle arrest in human A-375 cells assessed as accumulation at G0/G1 phase upto 1000 uM incubated for 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4734717 | F | Cytotoxicity against mouse B16F10 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4734721 | F | Cytotoxicity against human A375 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4734722 | B | Protac activity at CRBN/CDK2 in mouse B16F10 cells assessed as induction of CDK2 protein degradation after 12 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4734723 | B | Protac activity at CRBN/CDK4 in mouse B16F10 cells assessed as induction of CDK4 protein degradation after 12 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4734724 | B | Protac activity at CRBN/CDK6 in mouse B16F10 cells assessed as induction of CDK6 protein degradation after 12 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4734725 | B | Protac activity at CRBN/CDK2 in human A-375 cells assessed as induction of CDK2 protein degradation after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4734726 | B | Protac activity at CRBN/CDK4 in human A-375 cells assessed as induction of CDK4 protein degradation after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4734727 | B | Protac activity at CRBN/CDK6 in human A-375 cells assessed as induction of CDK6 protein degradation after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4734728 | B | Protac activity at CRBN/CDK2 in mouse B16F10 cells assessed as induction of CDK2 protein degradation at 500 nM by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4734729 | B | Protac activity at CRBN/CDK4 in mouse B16F10 cells assessed as induction of CDK4 protein degradation at 500 nM by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4734730 | B | Protac activity at CRBN/CDK6 in mouse B16F10 cells assessed as induction of CDK6 protein degradation at 500 nM by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4734731 | B | Protac activity at CRBN/CDK2 in human A-375 cells assessed as induction of CDK2 protein degradation at 1000 nM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4734732 | B | Protac activity at CRBN/CDK4 in human A-375 cells assessed as induction of CDK4 protein degradation at 1000 nM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4734733 | B | Protac activity at CRBN/CDK6 in human A-375 cells assessed as induction of CDK6 protein degradation at 1000 nM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4734734 | B | Protac activity at CRBN/CDK2 in mouse B16F10 cells assessed as induction of CDK2 protein degradation at 100 nM for 6 hrs in presence of proteasome inhibitor MG132 by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4734735 | B | Protac activity at CRBN/CDK4 in mouse B16F10 cells assessed as induction of CDK4 protein degradation at 100 nM for 6 hrs in presence of proteasome inhibitor MG132 by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4734736 | B | Protac activity at CRBN/CDK6 in mouse B16F10 cells assessed as induction of CDK6 protein degradation at 100 nM for 6 hrs in presence of proteasome inhibitor MG132 by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4734737 | F | Inhibition of colony formation in mouse B16F10 cells at 50 to 100 nM measured after 7 days by crystal violet staining based colony formation assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4734738 | F | Inhibition of colony formation in human A-375 cells at 250 to 500 nM measured after 7 days by crystal violet staining based colony formation assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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