| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4771737 | B | Inhibition of transport activity of human GLUT5 expressed in hexose transporter deficient VW4000 yeast cells assessed as reduction in transporter-mediated [14C]-fructose uptake into cells at 100 uM measured after 10 mins by scintillation counting method | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 2. | ALA4771744 | F | Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability measured after 48 hrs by Hoechst 33342/propidium iodide staining based imaging analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 3. | ALA4771745 | F | Cytotoxicity against human K562 cells assessed as reduction in cell viability measured after 48 hrs by Hoechst 33342/propidium iodide staining based imaging analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 4. | ALA4771746 | F | Cytotoxicity against human KCL-22 cells assessed as reduction in cell viability measured after 48 hrs by Hoechst 33342/propidium iodide staining based imaging analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA4771747 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by Hoechst 33342/propidium iodide staining based imaging analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA4771748 | A | Cytotoxicity against human HS27 cells assessed as reduction in cell viability measured after 48 hrs by Hoechst 33342/propidium iodide staining based imaging analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA4771751 | B | Inhibition of recombinant human His6/SUMO-tagged HDAC8 expressed in Escherichia coli (BL21) DE3 pLysS assessed as residual activity at 50 uM using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by fluorescence assay relative to control | Homo sapiens | 24 | assay format | Scientific Literature | ||
| 8. | ALA4771753 | B | Inhibition of recombinant human N-terminal GST-tagged HDAC4 (627 to end residues) expressed in baculovirus infected Sf9 insect cells assessed as residual activity at 50 uM using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by fluorescence assay relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature |
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