#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4668049	Binding	Selectivity index, ratio of IC50 for human serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's method to IC50 for human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's method	Homo sapiens	26	ALA4665668	assay format	Scientific Literature
2.	ALA4668050	Binding	Inhibition of human BACE-1 using MOCA-SEV-NL-DAEFR-DNP-RR as substrate preincubated with substrate followed by enzyme addition by FRET assay	Homo sapiens	31	ALA4665668	single protein format	Scientific Literature
3.	ALA4668051	Binding	Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's method	Homo sapiens	32	ALA4665668	cell-free format	Scientific Literature
4.	ALA4668052	Binding	Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's method	Homo sapiens	32	ALA4665668	tissue-based format	Scientific Literature
5.	ALA4668056	ADME	Permeability of the compound in PBS/EtOH buffer (7:3) at 25 ug/ml after 18 hrs by PAMPA-BBB assay		7	ALA4665668	assay format	Scientific Literature
6.	ALA4668057	Binding	Displacement of propidium iodide from PAS region of human erythrocytes AChE at 10 uM incubated for 6 hrs by fluorescence assay relative to control	Homo sapiens	7	ALA4665668	tissue-based format	Scientific Literature
7.	ALA4668058	Binding	Displacement of propidium iodide from PAS region of human erythrocytes AChE at 50 uM incubated for 6 hrs by fluorescence assay relative to control	Homo sapiens	7	ALA4665668	tissue-based format	Scientific Literature
8.	ALA4668059	Binding	Inhibition of amyloid beta (1 to 42) (unknown origin) self-induced aggregation assessed as normalized fluorescence intensity at 5 to 20 uM after 48 hrs by Thioflavin T based fluorometric assay	Homo sapiens	3	ALA4665668	single protein format	Scientific Literature
9.	ALA4668060	Binding	Inhibition of human erythrocytes AChE-induced amyloid beta (1 to 42) aggregation assessed as normalized fluorescence intensity at 5 to 20 uM after 48 hrs by thioflavin T-based fluorometric assay	Homo sapiens	3	ALA4665668	assay format	Scientific Literature
10.	ALA4668062	Functional	Neuroprotective activity against amyloid beta (1 to 42)-induced oxidative stress in human SH-SY5Y cells assessed as effect on cell viability at 10 to 80 uM measured after 24 hrs by MTT assay (Rvb = 61 %)	Homo sapiens	2	ALA4665668	cell-based format	Scientific Literature
11.	ALA4668063	Toxicity	Acute toxicity in Wistar rat assessed as abnormal signs at 100 to 500 mg/kg, po measured up to 14 days by OCED guideline method	Rattus norvegicus	2	ALA4665668	organism-based format	Scientific Literature
12.	ALA4668064	Toxicity	Acute toxicity in po dosed Wistar rat assessed as maximum tolerated dose by OCED guideline method	Rattus norvegicus	2	ALA4665668	organism-based format	Scientific Literature
13.	ALA4668066	Functional	Cognitive enhancing effect in po dosed scopolamine-induced Wistar rat model of amnesia assessed as increase in spontaneous alteration pretreated for 7 days followed by scopolamine challenge and measured after 30 mins by Y-maze test	Rattus norvegicus	2	ALA4665668	organism-based format	Scientific Literature
14.	ALA4668067	Functional	Cognitive enhancing effect in scopolamine-induced Wistar rat model of amnesia assessed as increase in spontaneous alteration at 10 mg/kg, po pretreated for 7 days followed by scopolamine challenge and measured after 30 mins by Y-maze test	Rattus norvegicus	1	ALA4665668	organism-based format	Scientific Literature