| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4775347 | Binding | Displacement of [125I] [NIe75, Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cell membranes incubated for 1 hr by gamma counting based Cheng-Prusoff equation analysis | Homo sapiens | 71 | ALA4765470 | cell-based format | Scientific Literature | |
| 2. | ALA4775348 | Binding | Agonist activity at human APJ receptor expressed in HEK293 cells co-expressing Galpha(i1)-RlucII(91) assessed as induction of dissociation of Galpha(i1) from G-beta-gamma subunits incubated for 5 mins by BRET assay | Homo sapiens | 23 | ALA4765470 | cell-based format | Scientific Literature | |
| 3. | ALA4775349 | Functional | Agonist activity at human APJ receptor expressed in HEK293T cells co-expressing PDZ-Rho-Gef-RLucll assessed as induction of Galpha12 effector (PDZ-RhoGEF) to the cell membrane incubated for 5 mins by BRET assay | Homo sapiens | 23 | ALA4765470 | cell-based format | Scientific Literature | |
| 4. | ALA4775351 | Binding | Agonist activity at human APJ receptor expressed in HEK293 cells co-expressing Rlucll-beta-arrestin2 assessed as induction of beta-arrestin2 recruitment to APJ incubated for 30 mins by BRET assay | Homo sapiens | 23 | ALA4765470 | cell-based format | Scientific Literature |
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