# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4700406 | F | Induction of apoptosis in human CAL-27 cells at 2.5 uM incubated for 48 hrs by annexin-V FITC and PI staining based flow cytometric analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA4700407 | F | Cytotoxicity against human CAL-27 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
3. | ALA4700408 | F | Cytotoxicity against human HEp-2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA4700409 | F | Cytotoxicity against human SCC-15 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA4700410 | A | Cytotoxicity against human OKF-6/TERT cells assessed as reduction in cell viability measured after 48 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA4700411 | T | Selectivity index, ratio of IC50 for human OKF-6/TERT cells to IC50 for human CAL27 cells after 48 hrs by MTT assay | 4 | assay format | Scientific Literature | |||
7. | ALA4700412 | T | Selectivity index, ratio of IC50 for human OKF-6/TERT cells to IC50 for human HEp-2 cells after 48 hrs by MTT assay | 4 | assay format | Scientific Literature | |||
8. | ALA4700413 | T | Selectivity index, ratio of IC50 for human OKF-6/TERT cells to IC50 for human SCC-15 cells after 48 hrs by MTT assay | 4 | assay format | Scientific Literature | |||
9. | ALA4700414 | F | Anticlonogenic activity against human CAL-27 cells assessed as reduction in colony formation incubated for 24 hrs followed supplementation with fresh medium without compound measured after 120 hrs by colony formation assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA4700415 | B | Induction of mitochondrial uncoupling in human CAL-27 cells assessed as oxygen consumption rate measured by Clark-type oxygen electrode method | Homo sapiens | 4 | mitochondrion format | Scientific Literature | ||
11. | ALA4700417 | F | Induction of mitochondrial membrane potential loss in human CAL-27 cells at 10 to 50 uM by flow cytometry | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
12. | ALA4700418 | F | Induction of mitochondrial membrane potential loss in human Hep-2 cells at 10 to 50 uM by flow cytometry | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA4700419 | F | Decrease in intracellular ATP levels in human CAL-27 cells at 10 to 50 uM incubated for 4 hrs by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA4700420 | F | Decrease in intracellular ATP levels in human Hep-2 cells at 10 to 50 uM incubated for 4 hrs by flow cytometry | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
15. | ALA4700421 | F | Induction of apoptosis in human Hep-2 cells at 2.5 uM incubated for 48 hrs by annexin-V FITC and PI staining based flow cytometric analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
16. | ALA4700422 | F | Induction of apoptosis in human CAL-27 cells assessed as increase in caspase 3 activity at 2.5 to 5 uM incubated for 24 hrs by flow cytometry | Homo sapiens | 4 | cell-based format | Scientific Literature |