# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4702670 | Functional | Antiviral activity against recombinant EGFP/RFP expressing Herpes simplex virus 1 KOS infected in iPSC-neurons assessed as decrease in proportion of fluorescent cells compound added 2 hr post infection incubated for 48 hrs by flow cytometry analysis | Human alphaherpesvirus 1 | 22 | ALA4699512 | organism-based format | Scientific Literature | |
2. | ALA4702671 | Functional | Antiviral activity against Herpes simplex virus 1 infected in neuronal progenitor cells assessed as decrease in fluorescent cells | Human alphaherpesvirus 1 | 2 | ALA4699512 | organism-based format | Scientific Literature | |
3. | ALA4702672 | ADME | Cytotoxicity against human neuronal progenitor cells assessed as cell viability at 25 uM | Homo sapiens | 1 | ALA4699512 | cell-based format | Scientific Literature | |
4. | ALA4702673 | Functional | Potency index, ratio of acyclovir IC50 to compound IC50 for antiviral activity against HSV-1 infected in neuronal progenitor cells | Human alphaherpesvirus 1 | 1 | ALA4699512 | organism-based format | Scientific Literature |