| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4722493 | T | Toxicity in human MDA-MB-435 cells assessed as mortality at 1 uM measured after 24 hrs by MTT assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA4722494 | T | Toxicity in human MDA-MB-435 cells assessed as mortality at 3 uM measured after 24 hrs by MTT assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 3. | ALA4722495 | T | Toxicity in human MDA-MB-435 cells assessed as mortality at 10 uM measured after 24 hrs by MTT assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 4. | ALA4722496 | T | Toxicity in human Huh-7 cells assessed as reduction in cell number after 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 5. | ALA4722497 | T | Toxicity in human Caco-2 cells assessed as reduction in cell number after 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 6. | ALA4722498 | T | Toxicity in human MDA-MB-231 cells assessed as reduction in cell number after 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA4722499 | T | Toxicity in human HCT-116 cells assessed as reduction in cell number after 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 8. | ALA4722500 | T | Toxicity in human PC-3 cells assessed as reduction in cell number after 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 9. | ALA4722501 | T | Toxicity in human NCI-H727 cells assessed as reduction in cell number after 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 10. | ALA4722502 | T | Toxicity in human MCF7 cells assessed as reduction in cell number after 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 11. | ALA4722503 | T | Toxicity in human skin fibroblasts assessed as reduction in cell number after 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 11 | tissue-based format | Scientific Literature | ||
| 12. | ALA4722504 | F | Antimetastatic activity against human MDA-MB-435 cells assessed as reduction in cell migration at 1 uM after 24 hrs by crystal violet staining based assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4722505 | F | Antimetastatic activity against human MDA-MB-435 cells harboring SK3 shRNA assessed as reduction in cell migration at 100 to 300 nM after 24 hrs by crystal violet staining based assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4722506 | F | Antimetastatic activity against human MDA-MB-435 cells harboring shRNA assessed as reduction in cell migration at 100 to 300 nM after 24 hrs by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4722510 | B | Inhibition of SK3/Orai1 in human MDA-MB-435 cells harboring SK3 shRNA assessed as reduction in Ca2+ influx at 300 nM measured after 1 hr by Fura2-AM dye based fluorescence assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4722511 | B | Inhibition of SK3 in human MDA-MB-435 cells harboring SK3 shRNA assessed as reduction in Ca2+ influx at 300 nM measured after 1 hr by Fura2-AM dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4722512 | F | Effect on calcium influx in human MDA-MB-435 cells harboring siRNA and siCTL at 300 nM measured after 1 hr by Fura2-AM dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4722513 | F | Effect on calcium influx in human MDA-MB-435 cells harboring siRNA and siOrai1 at 300 nM measured after 1 hr by Fura2-AM dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4722518 | B | Inhibition of SK3 (unknown origin) expressed in HEK293 cells assessed as reduction in channel current at 2 uM with 0 mV holding potential by patch clamp electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4722520 | B | Inhibition of SK3 (unknown origin) expressed in HEK293 cells assessed as reduction in channel current at 2 uM with 0 mV holding potential measured within 10 secs by patch clamp electrophysiological method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |
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