| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4726976 | Binding | Inhibition of recombinant GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after 30 min by liquid scintillation counting method | Homo sapiens | 9 | ALA4725285 | single protein format | Scientific Literature | |
| 2. | ALA4726977 | Binding | Inhibition of recombinant FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 30 min by liquid scintillation counting method | Homo sapiens | 9 | ALA4725285 | single protein format | Scientific Literature | |
| 3. | ALA4726978 | Binding | Selectivity ratio of IC50 for FDPS (unknown origin) to IC50 for GGDPS (unknown origin) | Homo sapiens | 9 | ALA4725285 | assay format | Scientific Literature | |
| 4. | ALA4726979 | Binding | Inhibition of GGDPS in human RPMI-8226 cells assessed as lowest effective concentration required to show unmodified Rap1a band after 48 hrs by immunoblot analysis | Homo sapiens | 9 | ALA4725285 | cell-based format | Scientific Literature | |
| 5. | ALA4726980 | Binding | Inhibition of GGDPS in human RPMI-8226 cells assessed as lowest effective concentration required for increase in intracellular lambda chain level after 48 hrs by ELISA | Homo sapiens | 9 | ALA4725285 | cell-based format | Scientific Literature |
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