# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4678157 | B | Induction of c-Myc degradation in human HL-60 cells assesses as decrease in c-Myc protein level measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4673326 | cell-based format | Scientific Literature | |
2. | ALA4678158 | F | Induction of apoptosis in human HL-60 cells at 1 to 20 uM measured after 24 hrs by FITC-Annexin-v/propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4673326 | cell-based format | Scientific Literature | |
3. | ALA4678159 | F | Cell cycle arrest in human HL-60 cells assessed as accumulation at S-phase at 3.125 to 6.25 uM measured after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4673326 | cell-based format | Scientific Literature | |
4. | ALA4678160 | B | Inhibition of Nanoluc-tagged c-Myc/Halo-tagged MAX (unknown origin) interaction expressed in HEK293T cells assessed as degradation measured after 4 to 6 hrs by NanoBRET assay | Homo sapiens | 1 | ALA4673326 | cell-based format | Scientific Literature | |
5. | ALA4678161 | F | Antiproliferative activity against human HL-60 cells assessed as inhibition of cell proliferation incubated for 72 hrs | Homo sapiens | 51 | ALA4673326 | cell-based format | Scientific Literature |