#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4685307	Binding	Inhibition of JAK3 in mouse T cells assessed as reduction in IL2-stimulated cell proliferation measured after 72 hrs by MTS assay	Mus musculus	4	ALA4680201	cell-based format	Scientific Literature
2.	ALA4685308	Binding	Inhibition of JAK3 in mouse T cells assessed as reduction in anti-CD3/-CD28-stimulated cell proliferation measured after 72 hrs by MTS assay	Mus musculus	4	ALA4680201	cell-based format	Scientific Literature
3.	ALA4685309	Binding	Inhibition of recombinant human GST-tagged JAK3 cytoplasmic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and measured after 30 mins by HTRF assay	Homo sapiens	40	ALA4680201	assay format	Scientific Literature
4.	ALA4685310	ADME	Inhibition of recombinant human GST-tagged JAK2 cytoplasmic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and measured after 30 mins by HTRF assay	Homo sapiens	40	ALA4680201	assay format	Scientific Literature
5.	ALA4685311	ADME	Inhibition of recombinant human GST-tagged JAK1 cytoplasmic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and measured after 30 mins by HTRF assay	Homo sapiens	40	ALA4680201	assay format	Scientific Literature
6.	ALA4685312	ADME	Inhibition of recombinant human N-terminal GST-tagged TYK2 cytoplasmic domain (833 to 1187 residues) expressed in baculovirus expression system using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and measured after 30 mins by HTRF assay	Homo sapiens	40	ALA4680201	assay format	Scientific Literature
7.	ALA4685313	Binding	Selectivity ratio of IC50 for inhibition of recombinant human GST-tagged JAK2 cytoplasmic domain (809 to 1153+9 residues) expressed in baculovirus expression system to IC50 for inhibition of recombinant human GST-tagged JAK3 cytoplasmic domain (781 to 1124 residues) expressed in baculovirus expression system	Homo sapiens	31	ALA4680201	assay format	Scientific Literature
8.	ALA4685314	Binding	Selectivity ratio of IC50 for inhibition of recombinant human GST-tagged JAK1 cytoplasmic domain (866 to 1154 residues) expressed in baculovirus expression system to IC50 for inhibition of recombinant human GST-tagged JAK3 cytoplasmic domain (781 to 1124 residues) expressed in baculovirus expression system	Homo sapiens	36	ALA4680201	assay format	Scientific Literature
9.	ALA4685316	ADME	Cytotoxicity against resting mouse T cells assessed as reduction in cell viability at 10 uM measured after 72 hrs by MTS assay	Mus musculus	3	ALA4680201	cell-based format	Scientific Literature
10.	ALA4685317	ADME	Cytotoxicity against IL-4-treated mouse T cells assessed as reduction in cell viability at 10 uM measured after 72 hrs by MTS assay	Mus musculus	3	ALA4680201	cell-based format	Scientific Literature
11.	ALA4685318	ADME	Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 10 uM measured after 72 hrs by MTS assay	Mus musculus	3	ALA4680201	cell-based format	Scientific Literature
12.	ALA4685319	Binding	Inhibition of JAK3 in anti-CD3/-CD28 coated mouse T cells assessed as reduction in IL2-induced STAT5 phosphorylation at 10 uM preincubated for 1 hr followed by IL2 stimulation and measured after 30 mins by Western blot analysis	Mus musculus	3	ALA4680201	tissue-based format	Scientific Literature
13.	ALA4685320	Binding	Inhibition of JAK3 in anti-CD3/-CD28 coated mouse T cells assessed as reduction in IL15-induced STAT5 phosphorylation at 10 uM preincubated for 1 hr followed by IL2 stimulation and measured after 30 mins by Western blot analysis	Mus musculus	3	ALA4680201	tissue-based format	Scientific Literature
14.	ALA4685351	Functional	Immunosuppressive activity in Balb/c mouse model of oxazolone-induced delayed type hypersensitivity assessed as reduction in spleen index at 30 mg/kg, po measured after 7 days	Mus musculus	4	ALA4680201	organism-based format	Scientific Literature