| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4775756 | Binding | Selectivity index, ratio of EC50 for agonist activity at human CB1 receptor expressing CHO cells co-expressing Galpha16 by calcium mobilization assay to EC50 for agonist activity at human CB2 receptor expressing CHO cells co-expressing Galpha16 by calcium mobilization assay | Homo sapiens | 1 | ALA4765487 | assay format | Scientific Literature | |
| 2. | ALA4775761 | Functional | Agonist activity at human CB1 receptor expressing CHO cells co-expressing Galpha16 by calcium mobilization assay | Homo sapiens | 52 | ALA4765487 | cell-based format | Scientific Literature | |
| 3. | ALA4775762 | Functional | Agonist activity at human CB1 receptor expressing CHO cells co-expressing Galpha16 by calcium mobilization assay relative to CP55940 | Homo sapiens | 52 | ALA4765487 | cell-based format | Scientific Literature | |
| 4. | ALA4775763 | Functional | Agonist activity at human CB2 receptor expressing CHO cells co-expressing Galpha16 by calcium mobilization assay | Homo sapiens | 52 | ALA4765487 | cell-based format | Scientific Literature | |
| 5. | ALA4775764 | Functional | Agonist activity at human CB2 receptor expressing CHO cells co-expressing Galpha16 by calcium mobilization assay relative to CP55940 | Homo sapiens | 52 | ALA4765487 | cell-based format | Scientific Literature | |
| 6. | ALA4775765 | Functional | Agonist activity at human CB2 receptor expressing CHO cells co-expressing Galpha16 in presence of CB2 antagonist AM630 by calcium mobilization assay | Homo sapiens | 1 | ALA4765487 | cell-based format | Scientific Literature | |
| 7. | ALA4775766 | ADME | Half life in human liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 8 | ALA4765487 | microsome format | Scientific Literature | |
| 8. | ALA4775767 | ADME | Intrinsic clearance in human liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 8 | ALA4765487 | microsome format | Scientific Literature | |
| 9. | ALA4775768 | ADME | Intrinsic clearance in human liver at 1 uM in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 8 | ALA4765487 | tissue-based format | Scientific Literature | |
| 10. | ALA4775769 | ADME | Stability in human liver microsomes assessed as parent compound remaining at 1 uM incubated for 60 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 8 | ALA4765487 | microsome format | Scientific Literature | |
| 11. | ALA4775770 | ADME | Cmax in BALB/c mouse at 1 mg/kg, iv measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature | |
| 12. | ALA4775771 | ADME | Cmax in BALB/c mouse at 5 mg/kg, po measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature | |
| 13. | ALA4775772 | ADME | AUC (0 to infinity) in BALB/c mouse at 1 mg/kg, iv measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature | |
| 14. | ALA4775773 | ADME | AUC (0 to infinity) in BALB/c mouse at 5 mg/kg, po measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature | |
| 15. | ALA4775774 | ADME | Volume of distribution in BALB/c mouse at 1 mg/kg, iv measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature | |
| 16. | ALA4775775 | ADME | Volume of distribution in BALB/c mouse at 5 mg/kg, po measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature | |
| 17. | ALA4775776 | ADME | Clearance in BALB/c mouse at 1 mg/kg, iv measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature | |
| 18. | ALA4775777 | ADME | Clearance in BALB/c mouse at 5 mg/kg, po measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature | |
| 19. | ALA4775778 | ADME | Half life in BALB/c mouse at 1 mg/kg, iv measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature | |
| 20. | ALA4775779 | ADME | Half life in BALB/c mouse at 5 mg/kg, po measured during 0.083 to 24 hrs post dose by LC-MS/MS analysis | Mus musculus | 1 | ALA4765487 | organism-based format | Scientific Literature |
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