#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4669200	Binding	Potency index, ratio of (R)-MB001 EC50 to test compound EC50 for inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated with enzyme for 5 mins followed by further incubation with all-trans-retinol for 1 hr by normal phase HPLC analysis	Bos taurus	2	ALA4665714	microsome format	Scientific Literature
2.	ALA4669201	Binding	Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated with enzyme for 5 mins followed by further incubation with all-trans-retinol for 1 hr by normal phase HPLC analysis	Bos taurus	3	ALA4665714	microsome format	Scientific Literature
3.	ALA5032820	Binding	Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by normal phase HPLC analysis	Bos taurus	18	ALA5032497	microsome format	Scientific Literature
4.	ALA5032821	ADME	Drug distribution in wild type BL/6J mouse eyes measured at 380 nM, IP administered single dose per eye after 3 hrs by LC-MS/MS electrospray ionization fragmentation spectra method	Mus musculus	4	ALA5032497	tissue-based format	Scientific Literature
5.	ALA5032822	ADME	Drug distribution in wild type BL/6J mouse eyes measured at 380 nM, IP administered single dose per eye after 24 hrs by LC-MS/MS electrospray ionization fragmentation spectra method	Mus musculus	1	ALA5032497	tissue-based format	Scientific Literature