| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4716053 | B | Inhibition of CutC in Escherichia coli MS 200-1 assessed as reduction in d9-TMA formation using d9-choline chloride as substrate incubated for 4 hrs under anaerobic condition by LC-MS-MS analysis | Escherichia coli | 16 | assay format | Scientific Literature | ||
| 2. | ALA4716054 | B | Inhibition of N-terminal His6-tagged Desulfovibrio desulfuricans G20 CutC encoding 52 residues assessed as reduction in acetaldehyde using choline as substrate in presence of NADH-dependent yeast alcohol dehydrogenase by UV-Vis absorbance based assay | Desulfovibrio desulfuricans | 17 | single protein format | Scientific Literature | ||
| 3. | ALA4716055 | B | Binding affinity to CutC (unknown origin) by CM5 sensor chip immobilization based surface plasmon resonance analysis | Bacteria | 1 | assay format | Scientific Literature | ||
| 4. | ALA4716056 | B | Non-competitive inhibition of CutC (unknown origin) assessed as reduction in Vmax with constant Km using choline as substrate at 5 uM by Lineweaver-Burk plot based Michelis-Menten analysis | Bacteria | 1 | assay format | Scientific Literature | ||
| 5. | ALA4716057 | B | Inhibition of Proteus mirabilis CutC assessed as reduction in d9-TMA formation using d9-choline chloride as substrate at 10 uM incubated for 4 hrs under anaerobic condition by LC-MS-MS analysis | Proteus mirabilis | 2 | assay format | Scientific Literature | ||
| 6. | ALA4716058 | B | Inhibition of CutC in Clostridium sporogenes assessed as reduction in d9-TMA formation using d9-choline chloride as substrate at 10 uM incubated for 4 hrs under anaerobic condition by LC-MS-MS analysis | Clostridium sporogenes | 2 | assay format | Scientific Literature | ||
| 7. | ALA4716059 | B | Inhibition of Klebsiella sp. MS92-3 CutC assessed as reduction in d9-TMA formation using d9-choline chloride as substrate at 10 uM incubated for 4 hrs under anaerobic condition by LC-MS-MS analysis | Klebsiella sp. | 2 | assay format | Scientific Literature | ||
| 8. | ALA4716060 | B | Inhibition of Escherichia coli MS 200-1 CutC assessed as reduction in d9-TMA formation using d9-choline chloride as substrate at 10 uM incubated for 4 hrs under anaerobic condition by LC-MS-MS analysis | Escherichia coli | 2 | assay format | Scientific Literature | ||
| 9. | ALA4716061 | B | Inhibition of CutC (unknown origin) in human feces assessed as reduction in TMA production using choline as substrate by LC-MS/MS analysis | Bacteria | 2 | tissue-based format | Scientific Literature | ||
| 10. | ALA4716062 | A | Metabolic stability in human intestinal S9 fraction assessed as parent compound remaining at 33 uM incubated for 2 hrs by LC/MS/MS analysis | Homo sapiens | 15 | subcellular format | Scientific Literature | ||
| 11. | ALA4716063 | F | Effect on d9-choline uptake in Escherichia coli MS 200-1 at 50 uM incubated for 15 mins by LC-MS/MS analysis | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 12. | ALA4716064 | B | Effect on alcohol dehydrogenase activity in yeast at 5 to 50 uM in presence of NADPH by colorimetric assay | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 13. | ALA4716065 | B | Binding affinity to CutD (unknown origin) by CM5 sensor chip immobilization based surface plasmon resonance analysis | Bacteria | 1 | assay format | Scientific Literature |
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