# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4724224 | B | Inhibition of HER2 in human AU565 cells assessed as reduction in ERK phosphorylation at IC50 incubated for 24 hrs by western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA4724225 | B | Inhibition of HER2 in human AU565 cells assessed as reduction in ERK phosphorylation at IC50 incubated for 72 hrs by western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA4724226 | B | Inhibition of HER2 in human AU565 cells assessed as reduction in Akt phosphorylation at IC50 incubated after 24 to 72 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA4724231 | F | Induction of apoptosis in human BT474 cells assessed as increase in late apoptotic cells at 0.5 to 5 uM incubated for 72 hrs by Annexin V-FITC/PI staining based flow cytometry analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4724232 | F | Induction of apoptosis in human BT474 cells assessed as increase in early apoptotic cells at 0.5 to 5 uM incubated for 72 hrs by Annexin V-FITC/PI staining based flow cytometry analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA4724234 | F | Induction of apoptosis in human BT474 cells assessed as increase in early apoptotic cells incubated for 72 hrs by Annexin V-FITC/PI staining based flow cytometry analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA4724249 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by WST8 assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
8. | ALA4724250 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by WST8 assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
9. | ALA4724280 | F | Antiproliferative activity against human BT474 cells assessed as reduction in cell viability incubated for 72 hrs by WST8 assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
10. | ALA4724281 | F | Antiproliferative activity against human AU565 cells assessed as reduction in cell viability incubated for 72 hrs by WST8 assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
11. | ALA4724283 | F | Selectivity ratio of IC50 for antiproliferative activity against human AU565 cells to IC50 for antiproliferative activity against human BT474 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4724284 | F | Potency index, ratio of lapatinib IC50 to test compound IC50 for antiproliferative activity against human MCF7 cells | Homo sapiens | 8 | cell-based format | Scientific Literature |