# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4687984 | Binding | Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H] cholesteryl oleate or [3H] triolein between exogenous LDL and HDL in 2% human serum | Homo sapiens | 22 | ALA4680288 | single protein format | Scientific Literature | |
2. | ALA4687985 | Binding | Inhibition of CETP in 95% human serum assessed as inhibition of transfer of [3H] cholesteryl oleate or [3H] triolein between LDL and HDL | Homo sapiens | 22 | ALA4680288 | cell-free format | Scientific Literature | |
3. | ALA4687986 | Functional | In vivo inhibition of CETP in cynomolgus-CETP transgenic mouse assessed as increase in plasma HDL-C level at 1 mg/kg, po measured after 4 hrs | Mus musculus | 4 | ALA4680288 | organism-based format | Scientific Literature | |
4. | ALA4687988 | ADME | Plasma concentration in cynomolgus-CETP transgenic mouse at 1 mg/kg, po measured after 4 hrs | Mus musculus | 4 | ALA4680288 | organism-based format | Scientific Literature | |
5. | ALA4687990 | Functional | In vivo inhibition of CETP in cynomolgus-CETP transgenic mouse plasma at 1 mg/kg, po measured after 4 hrs | Mus musculus | 4 | ALA4680288 | organism-based format | Scientific Literature |