| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4669513 | B | Modulation of human ERG | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA4669514 | F | Antiviral activity against Middle East respiratory syndrome coronavirus MERS-CoV/KOR/KNIH/002_05_2015 infected in African green monkey Vero cells assessed as reduction in virus induced cytopathic effect after 24 hrs by immunofluorescence assay | Middle East respiratory syndrome-related coronavirus | 31 | organism-based format | Scientific Literature | ||
| 3. | ALA4669515 | A | Cytotoxicity against African green monkey Vero cells infected with Middle East respiratory syndrome coronavirus MERS-CoV/KOR/KNIH/002_05_2015 assessed as reduction in cell viability | Chlorocebus sabaeus | 31 | cell-based format | Scientific Literature | ||
| 4. | ALA4669516 | U | Selectivity index, ratio of CC50 for African green monkey Vero cells infected with Middle East respiratory syndrome coronavirus MERS-CoV/KOR/KNIH/002_05_2015 assessed as reduction in cell viability to IC50 for antiviral activity against Middle East respiratory syndrome coronavirus MERS-CoV/KOR/KNIH/002_05_2015 infected in African green monkey Vero cells assessed as reduction in virus induced cytopathic effect after 24 hrs by immunofluorescence assay | 31 | assay format | Scientific Literature | |||
| 5. | ALA4669517 | A | Metabolic stability in mouse microsomes assessed as parent compound remaining incubated for 30 mins | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 6. | ALA4669518 | A | Metabolic stability in human microsomes assessed as parent compound remaining incubated for 30 mins | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 7. | ALA4669519 | A | Cytotoxicity against African green monkey Vero cells | Chlorocebus sabaeus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4669520 | A | Cytotoxicity against human HFL-1 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4669521 | A | Cytotoxicity against mouse L929 cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4669522 | A | Cytotoxicity against mouse NIH/3T3 cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4669523 | A | Cytotoxicity against CHO-K1 cells | Cricetulus griseus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4669524 | A | Half life in rat at 2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4669525 | A | AUC in rat at 2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4669526 | A | Clearance in rat at 2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4669527 | A | Volume of distribution at steady state in rat at 2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4669528 | A | Tmax in rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4669529 | A | Cmax in rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4669530 | A | Half life in rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4669531 | A | AUC in rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4669532 | A | Oral bioavailability in rat at 5 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!