| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4675809 | Binding | Inhibition of recombinant human His-tagged TYK2 expressed in baculovirus infected Sf21 cells using 5FAM-KKSRGDYMTMQID as substrate in presence of ATP at Km by microfluidic assay | Homo sapiens | 21 | ALA4673239 | cell-based format | Scientific Literature | |
| 2. | ALA4675810 | Physicochemical | Octanol/water phosphate buffer partition coefficient, log D of compound at pH 7.4 by shake-flask method | 21 | ALA4673239 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA4675811 | ADME | Apparent permeability in MDCK-II cells | Canis lupus familiaris | 18 | ALA4673239 | cell-based format | Scientific Literature | |
| 4. | ALA4675812 | ADME | Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using 5FAM-KKSRGDYMTMQID as substrate in presence of ATP at Km by microfluidic assay | Homo sapiens | 18 | ALA4673239 | assay format | Scientific Literature | |
| 5. | ALA4675813 | ADME | Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using FITC-KGGEEEEYFELVKK as substrate in presence of ATP at Km by microfluidic assay | Homo sapiens | 18 | ALA4673239 | assay format | Scientific Literature | |
| 6. | ALA4675814 | Binding | Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using FITC-KGGEEEEYFELVKK as substrate in presence of ATP at Km by microfluidic assay | Homo sapiens | 18 | ALA4673239 | assay format | Scientific Literature | |
| 7. | ALA4675815 | ADME | Clearance in human liver microsomes assessed per mg protein | Homo sapiens | 18 | ALA4673239 | microsome format | Scientific Literature |
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