# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4736172 | Binding | Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells assessed as residual activity at 1 uM using d-erythro-sphingosine as substrate measured after 20 mins in presence of [gamma-32P]ATP by liquid scintillation counting analysis relative to control | Homo sapiens | 21 | ALA4732143 | cell-based format | Scientific Literature | |
2. | ALA4736173 | Binding | Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells assessed as residual activity at 0.3 uM using d-erythro-sphingosine as substrate measured after 20 mins in presence of [gamma-32P]ATP by liquid scintillation counting analysis relative to control | Homo sapiens | 21 | ALA4732143 | cell-based format | Scientific Literature | |
3. | ALA4736174 | Binding | Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 mins in presence of [gamma-32P]ATP by liquid scintillation counting analysis | Homo sapiens | 6 | ALA4732143 | cell-based format | Scientific Literature | |
4. | ALA4736175 | Binding | Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 mins in presence of [gamma-32P]ATP by liquid scintillation counting analysis | Homo sapiens | 6 | ALA4732143 | cell-based format | Scientific Literature | |
5. | ALA4736176 | Binding | Selectivity ratio of Ki for inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells to Ki for inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 6 | ALA4732143 | cell-based format | Scientific Literature |