# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4775272 | Functional | Anticoagulant activity in human plasma assessed prothrombin time at 0.25 to 1 uM | Homo sapiens | 9 | ALA4765467 | cell-free format | Scientific Literature | |
2. | ALA4775273 | Physicochemical | Thermodynamic stability assessed as change in melting temperature by CD spectroscopy relative to TBA | 8 | ALA4765467 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4775275 | ADME | Stability in 50% human plasma assessed as compound degradation at 50 uM measured within 3 hrs by PAGE analysis | Homo sapiens | 9 | ALA4765467 | cell-free format | Scientific Literature | |
4. | ALA4775276 | Functional | Anticoagulant activity in human plasma assessed prothrombin time in presence of complementary sequence of TBA | Homo sapiens | 3 | ALA4765467 | cell-free format | Scientific Literature | |
5. | ALA4775277 | Functional | Anticoagulant activity in human plasma assessed prothrombin time in presence of 1.5 fold complementary sequence of TBA | Homo sapiens | 4 | ALA4765467 | cell-free format | Scientific Literature | |
6. | ALA4775278 | Functional | Anticoagulant activity in ferric chloride-induced Sprague-Dawley rat carotid thrombosis model assessed as reduction in thrombus formation by measuring thrombus area at 2 mmol/kg, iv by H and E staining based analysis | Rattus norvegicus | 1 | ALA4765467 | organism-based format | Scientific Literature |