# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4731698 | B | Inhibition of full length C-terminal His/FLAG-tagged human HDAC1 expressed in baculovirus expression system using ZMAL as substrate incubated for 90 mins by fluorescence assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
2. | ALA4731699 | B | Inhibition of full length N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using ZMAL as substrate incubated for 90 mins by fluorescence assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
3. | ALA4731700 | B | Selectivity ratio of IC50 for full length C-terminal His/FLAG-tagged human HDAC1 expressed in baculovirus expression system to IC50 full length N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system | Homo sapiens | 12 | assay format | Scientific Literature | ||
4. | ALA4731706 | F | Antiproliferative activity against human KYSE520 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue dye based spectrofluorometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA4731707 | F | Antiproliferative activity against human OE33 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA4731708 | F | Antiproliferative activity against human Ca9-22 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue dye based spectrofluorometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
7. | ALA4731709 | F | Antiproliferative activity against human TR-146 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue dye based spectrofluorometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
8. | ALA4731716 | F | Cell cycle arrest in human NB-4 cells at 5 to 10 uM measured after 24 to 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA4731718 | B | Inhibition of HDAC6 in human NB-4 cells assessed as increase in tubulin acetylation at 10 uM measured after 24 to 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA4731719 | A | Inhibition of HDAC in human NB-4 cells assessed as effect on histone acetylation at 10 uM measured after 24 to 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA4731720 | F | Induction of apoptosis in human NB-4 cells assessed as increase in cleaved PARP expression at 10 uM measured after 24 to 48 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |