#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4724191	A	Metabolic stability in CD-1 mouse liver microsomes assessed as parent compound remaining at 100 uM measured after 60 mins by LC-MS/MS analysis	Mus musculus	5	ALA4715878	microsome format	Scientific Literature
2.	ALA4724192	A	Metabolic stability in CD-1 mouse liver microsomes assessed as parent compound remaining at 100 uM measured after 60 mins in presence of NADPH by LC-MS/MS analysis	Mus musculus	5	ALA4715878	microsome format	Scientific Literature
3.	ALA4724193	A	Intrinsic clearance in CD-1 mouse liver microsomes at 100 uM measured after 60 mins in presence of NADPH by LC-MS/MS analysis	Mus musculus	5	ALA4715878	microsome format	Scientific Literature
4.	ALA4724194	A	Intrinsic clearance in CD-1 mouse microsomes at 100 uM measured after 60 mins in presence of NADPH by LC-MS/MS analysis	Mus musculus	5	ALA4715878	microsome format	Scientific Literature
5.	ALA4724195	A	Metabolic stability in CD-1 mouse liver microsomes assessed as half-life at 100 uM measured after 60 mins in presence of NADPH by LC-MS/MS analysis	Mus musculus	5	ALA4715878	microsome format	Scientific Literature
6.	ALA4724196	F	Antitumor activity against human BT474 cells xenografted in athymic nude mouse assessed as reduction in metastasis of cells at 50 mg/kg, po administered via oral gavage for 5 times per week for 55 days measured post-last dose	Homo sapiens	2	ALA4715878	organism-based format	Scientific Literature
7.	ALA4724197	F	Antitumor activity against human BT474 cells xenografted in athymic nude mouse assessed as suppression of tumor growth by measuring decrease in number of Ki67 positive cells at 50 mg/kg, po administered via oral gavage for 5 times per week for 55 days measured post-last dose by Ki67-staining based immunohistochemistry	Homo sapiens	2	ALA4715878	organism-based format	Scientific Literature
8.	ALA4724198	F	Antitumor activity against human BT474 cells xenografted in athymic nude mouse assessed as inflammation in tumors at 50 mg/kg, po administered via oral gavage for 5 times per week for 55 days measured post-last dose by H and E staining based immunohistochemical analysis	Homo sapiens	2	ALA4715878	organism-based format	Scientific Literature
9.	ALA4724199	F	Antitumor activity against human BT474 cells xenografted in athymic nude mouse assessed as appearance of tumor fibrosis at 50 mg/kg, po administered via oral gavage for 5 times in a week for 55 days measured post-last dose by H and E staining based immunohistochemical analysis	Homo sapiens	2	ALA4715878	organism-based format	Scientific Literature
10.	ALA4724200	F	Antitumor activity against human BT474 cells xenografted in athymic nude mouse assessed as tumor necrosis at 50 mg/kg, po administered via oral gavage for 5 times in a week for 55 days measured post-last dose by H and E staining based immunohistochemical analysis	Homo sapiens	2	ALA4715878	organism-based format	Scientific Literature
11.	ALA4724201	F	Antitumor activity against human BT474 cells xenografted in athymic nude mouse assessed as tumor weight at 50 mg/kg, po administered via oral gavage for 5 times in a week for 55 days measured post last dose (Rvb = 2.046 g)	Homo sapiens	2	ALA4715878	organism-based format	Scientific Literature
12.	ALA4724202	F	Antitumor activity against human BT474 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 50 mg/kg, po administered via oral gavage for 5 times in a week for 55 days measured post last dose	Homo sapiens	2	ALA4715878	organism-based format	Scientific Literature
13.	ALA4724211	B	Inhibition of HER2 in human BT474 cells assessed as reduction in Erk1/2 phosphorylation at 0.5 IC50 incubated for 24 to 48 hrs by western blot analysis	Homo sapiens	1	ALA4715878	cell-based format	Scientific Literature
14.	ALA4724212	B	Inhibition of HER2 in human BT474 cells assessed as reduction in Erk1/2 phosphorylation at 0.1 IC50 incubated for 24 to 48 hrs by western blot analysis	Homo sapiens	1	ALA4715878	cell-based format	Scientific Literature
15.	ALA4724213	B	Inhibition of HER2 in human BT474 cells assessed as reduction in Akt phosphorylation at 0.5 IC50 incubated for 24 to 48 hrs by western blot analysis	Homo sapiens	1	ALA4715878	cell-based format	Scientific Literature
16.	ALA4724214	B	Inhibition of HER2 in human BT474 cells assessed as reduction in Akt phosphorylation at 0.1 IC50 incubated for 24 to 48 hrs by western blot analysis	Homo sapiens	1	ALA4715878	cell-based format	Scientific Literature
17.	ALA4724215	B	Inhibition of HER2 in human BT474 cells assessed as reduction in Akt phosphorylation at 0.1 IC50 after 24 to 48 hrs by Western blot analysis	Homo sapiens	1	ALA4715878	cell-based format	Scientific Literature
18.	ALA4724216	B	Inhibition of HER2 in human BT474 cells assessed as reduction in Akt phosphorylation at 0.5 IC50 after 24 to 48 hrs by Western blot analysis	Homo sapiens	1	ALA4715878	cell-based format	Scientific Literature
19.	ALA4724217	F	Down regulation of HER2 expression in human BT474 cells at 0.1 IC50 after 24 to 48 hrs by Western blot analysis	Homo sapiens	1	ALA4715878	cell-based format	Scientific Literature
20.	ALA4724218	F	Down regulation of HER2 expression in human BT474 cells at 0.5 IC50 after 24 to 48 hrs by Western blot analysis	Homo sapiens	1	ALA4715878	cell-based format	Scientific Literature