| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4676055 | Binding | Inhibition of 1 nM recombinant human N-terminal His-tagged KHKC expressed in Escherichia coli BL21 (DE3) using fructose as substrate preincubated for 30 mins followed by ATP addition and measured for 3 hrs by pyruvate kinase-lactate dehydrogenase coupled assay | Homo sapiens | 3 | ALA4673244 | assay format | Scientific Literature | |
| 2. | ALA4676056 | Physicochemical | Lipophilicity, log D of the compound at pH 7.4 by shake flask method | 6 | ALA4673244 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA4676058 | ADME | Apparent clearance in human hepatocytes assessed per million cells | Homo sapiens | 3 | ALA4673244 | cell-based format | Scientific Literature | |
| 4. | ALA4676059 | ADME | Apparent permeability in MDCK-II cells | Canis lupus familiaris | 4 | ALA4673244 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!