# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4686908 | Binding | Antagonist activity at NMDAR in embryonic cultures of rat cortical neuron assessed as inhibition of NMDA-induced calcium influx at 30 uM preincubated for 10 mins followed by NMDA addition by Fluo-4/AM dye based fluorescence assay relative to control | Rattus norvegicus | 18 | ALA4680250 | tissue-based format | Scientific Literature | |
2. | ALA4686909 | Binding | Antagonist activity at NMDAR in embryonic cultures of rat cortical neuron assessed as inhibition of NMDA-induced calcium influx preincubated for 10 mins followed by NMDA addition by Fluo-4/AM dye based fluorescence assay | Rattus norvegicus | 12 | ALA4680250 | tissue-based format | Scientific Literature | |
3. | ALA4686910 | ADME | Cytotoxicity against HEK293 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 12 | ALA4680250 | cell-based format | Scientific Literature | |
4. | ALA4686911 | ADME | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 12 | ALA4680250 | cell-based format | Scientific Literature | |
5. | ALA4686912 | ADME | Permeability of compound in PBS at pH 7.4 incubated for 120 mins by UV spectroscopy assay based PAMPA-BBB assay | 5 | ALA4680250 | assay format | Scientific Literature |