| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4709161 | B | Inhibition of human His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl measured for 12 mins by fluorescence incision assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4709162 | B | Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells by steady-state fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4709163 | B | Binding affinity to 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl (unknown origin) measured for 12 mins by fluorescence incision assay | Not specified | 3 | assay format | Scientific Literature | ||
| 4. | ALA4709164 | B | Inhibition of human His-tagged ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl at 10 uM measured for 12 mins by fluorescence incision assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 5. | ALA4709165 | B | Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells at 4 uM by steady-state fluorescence assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4709167 | A | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability at 5 to 20 uM after 3 days | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4709174 | F | Antiproliferative activity against human HCT-116 cells assessed as sensitizing capacity by measuring reduction in cell survival at 4 uM in presence of cyclophosphamide by clonogenic survival assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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