# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4714596 | Binding | Inhibition of human RFC expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTiter-blue assay | Homo sapiens | 8 | ALA4706714 | cell-based format | Scientific Literature | |
2. | ALA4714597 | ADME | Cytotoxicity against Chinese Hamster MTXRII-OuaR2-4 R2 cells cells assessed as reduction in cell proliferation after 96 hrs by CellTiter-blue assay | Cricetulus griseus | 8 | ALA4706714 | cell-based format | Scientific Literature | |
3. | ALA4714598 | Binding | Inhibition of human FRalpha expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTiter-blue assay | Homo sapiens | 8 | ALA4706714 | cell-based format | Scientific Literature | |
4. | ALA4714599 | Binding | Inhibition of human FRbeta expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTiter-blue assay | Homo sapiens | 8 | ALA4706714 | cell-based format | Scientific Literature | |
5. | ALA4714600 | Binding | Inhibition of human PCFT expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTiter-blue assay | Homo sapiens | 8 | ALA4706714 | cell-based format | Scientific Literature | |
6. | ALA4714601 | Functional | Antiproliferative activity against human KB cells assessed as reduction in cell viability after 96 hrs by CellTiter-blue assay | Homo sapiens | 8 | ALA4706714 | cell-based format | Scientific Literature | |
7. | ALA4714602 | Functional | Antiproliferative activity against human KB cells assessed as reduction in cell viability after 96 hrs in presence of folic acid by CellTiter-blue assay | Homo sapiens | 8 | ALA4706714 | cell-based format | Scientific Literature | |
8. | ALA4714603 | Functional | Antiproliferative activity against human IGROV1 cells assessed as reduction in cell viability after 96 hrs by CellTiter-blue assay | Homo sapiens | 8 | ALA4706714 | cell-based format | Scientific Literature | |
9. | ALA4714604 | Functional | Antiproliferative activity against human IGROV1 cells assessed as reduction in cell viability after 96 hrs in presence of folic acid by CellTiter-blue assay | Homo sapiens | 8 | ALA4706714 | cell-based format | Scientific Literature | |
10. | ALA4714607 | Binding | Inhibition of human full length N-terminal His-tagged GARFTase expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in THF formation using 10-CHOTHF as substrate by spectrophotometric method | Homo sapiens | 10 | ALA4706714 | cell-based format | Scientific Literature | |
11. | ALA4714608 | Binding | Inhibition of human full length N-terminal His-tagged ATIC expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in THF formation using 10-CHOTHF as substrate by spectrophotometric method | Homo sapiens | 10 | ALA4706714 | cell-based format | Scientific Literature | |
12. | ALA4714609 | Functional | Antiproliferative activity against human KB cells assessed as reduction in cell viability after 96 hrs in presence of thymidine by CellTiter-blue assay | Homo sapiens | 9 | ALA4706714 | cell-based format | Scientific Literature | |
13. | ALA4714610 | Functional | Antiproliferative activity against human KB cells assessed as reduction in cell viability after 96 hrs in presence of adenosine by CellTiter-blue assay | Homo sapiens | 9 | ALA4706714 | cell-based format | Scientific Literature |