| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4739266 | F | Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA4739267 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4739268 | F | Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA4739269 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA4739270 | F | Cytotoxicity in human J82 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA4739271 | A | Cytotoxicity against HUVEC assessed as reduction in cell viability by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA4739272 | U | Selectivity index ratio of IC50 for HUVEC to IC50 for human OVCAR3 cells | 1 | assay format | Scientific Literature | |||
| 8. | ALA4739273 | F | Induction of apoptosis in human OVCAR-3 cells assessed as early apoptotic cell at 10 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 1.58%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4739274 | F | Induction of apoptosis in human OVCAR-3 cells assessed as late apoptotic cell at 10 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 0.118%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4739275 | F | Induction of apoptosis in human OVCAR-3 cells assessed as necrotic cell at 10 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 0.00%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4739276 | F | Induction of apoptosis in human OVCAR-3 cells assessed as viable cell at 10 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 98.3%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4739277 | F | Induction of apoptosis in human OVCAR-3 assessed as nuclear blebbing measured after 48 hrs by Hoechst 33258 staining based fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4739278 | F | Induction of apoptosis in human OVCAR-3 assessed as nuclear rounding measured after 48 hrs by Hoechst 33258 staining based fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4739279 | F | Induction of mitochondrial membrane potential loss in human OVCAR-3 cells assessed as mitochondrial depolarization by measuring green fluorescence at 3 uM measured after 48 hrs by JCI staining based fluorescence microscopy (Rvb = 3.3 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4739280 | F | Induction of mitochondrial membrane potential loss in human OVCAR-3 cells assessed as mitochondrial depolarization by measuring green fluorescence at 10 uM measured after 48 hrs by JCI staining based fluorescence microscopy (Rvb = 3.3 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4739281 | F | Induction of mitochondrial membrane potential loss in human OVCAR-3 cells assessed as mitochondrial depolarization by measuring green fluorescence at 30 uM measured after 48 hrs by JCI staining based fluorescence microscopy (Rvb = 3.3 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4739282 | B | Induction of heme-mediated cell death in human OVCAR-3 cells assessed as reduction in cell viability at 3 to 30 uM pretreated with delta-aminolevulinic acid followed by compound addition by Hoechst 33258 staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4739283 | B | Induction of heme-mediated cell death in human OVCAR-3 cells assessed as reduction in cell viability at 3 to 30 uM pretreated with succinyl-acetone followed by compound addition by Hoechst 33258 staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4739288 | F | Induction of apoptosis in human OVCAR-3 assessed as nuclear shrinkage measured after 48 hrs by Hoechst 33258 staining based fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4739289 | F | Potency index, ratio of cisplatin IC50 to test compound IC50 for human A549 cells | Homo sapiens | 2 | cell-based format | Scientific Literature |
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