| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4688262 | B | Displacement of fluorescent labeled probe from human recombinant His-tagged TNFalpha (77 to 233 residues) expressed in Escherichia coli preincubated for 1 hr followed by fluorogenic probe addition and measured after 3 hrs by HTRF assay | Homo sapiens | 36 | ALA4680302 | assay format | Scientific Literature | |
| 2. | ALA4688263 | B | Inhibition of exogenous human TNFalpha in HEK-Blue-CD40L cells assessed as reduction in TNF-alpha-induced NFkappaB activation incubated for 18 hrs by quanti-blue based SEAP assay | Homo sapiens | 37 | ALA4680302 | cell-based format | Scientific Literature | |
| 3. | ALA4688264 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining after 10 mins | Homo sapiens | 34 | ALA4680302 | microsome format | Scientific Literature | |
| 4. | ALA4688265 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining after 10 mins | Mus musculus | 34 | ALA4680302 | microsome format | Scientific Literature |
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