# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4700038 | Binding | Binding affinity to EPHA3 (unknown origin) assessed as increase in change in melting temperature by differential scanning fluorimetric analysis | Homo sapiens | 2 | ALA4699412 | single protein format | Scientific Literature | |
2. | ALA4700039 | Binding | Inhibition of full-length human EPHB4 expressed in MEF cells assessed as autophosphorylation by sandwitch-ELISA | Homo sapiens | 2 | ALA4699412 | cell-based format | Scientific Literature | |
3. | ALA4700040 | Functional | Growth inhibition of human SU-DHL-2 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | tissue-based format | Scientific Literature | |
4. | ALA4700041 | Functional | Growth inhibition of human MAVER-1 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | cell-based format | Scientific Literature | |
5. | ALA4700064 | Functional | Growth inhibition of human Jeko-1 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | cell-based format | Scientific Literature | |
6. | ALA4700065 | Functional | Growth inhibition of human MEC-1 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | tissue-based format | Scientific Literature | |
7. | ALA4700066 | Functional | Growth inhibition of human PCL12 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | tissue-based format | Scientific Literature | |
8. | ALA4700067 | Functional | Growth inhibition of human Ri1 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | tissue-based format | Scientific Literature | |
9. | ALA4700070 | Toxicity | Toxicity in NOD-SCID nude mouse xenografted with human Ri1 cells assessed as body weight loss at 100 mg/kg, ip daily for 5 days | Mus musculus | 1 | ALA4699412 | organism-based format | Scientific Literature | |
10. | ALA4700071 | Functional | Antitumor activity against human Ri1 cells xenografted in NOD-SCID mouse assessed as fold change in tumor size at 100 mg/kg, ip administered for 2 weeks by caliper method relative to control | Homo sapiens | 1 | ALA4699412 | organism-based format | Scientific Literature |