| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4667665 | A | Metabolic stability in human microsome assessed as half life | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 2. | ALA4667666 | P | Aqueous solubility of the compound at pH 7 | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4667667 | A | Metabolic stability in mouse microsome assessed as half life | Mus musculus | 3 | microsome format | Scientific Literature | ||
| 4. | ALA4667668 | A | AUC (0 to infinity) in mouse at 1 mg/kg, iv or 5 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 5. | ALA4667669 | B | Inhibition of MALT1 (unknown origin) by Glosensor reporter gene assay | Homo sapiens | 28 | single protein format | Scientific Literature | ||
| 6. | ALA4667670 | F | Antiproliferative activity against human OCILY3 cells by cell proliferation assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 7. | ALA4667671 | A | Plasma protein binding in mouse assessed as unbound fraction | Mus musculus | 3 | cell-free format | Scientific Literature | ||
| 8. | ALA4667672 | A | Clearance in mouse at 1 mg/kg, iv | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA4667673 | A | Half life in mouse at 1 mg/kg, iv or 5 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA4667674 | A | Oral bioavailability in mouse at 5 mg/kg | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA4667675 | A | Plasma protein binding in human assessed as unbound fraction | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
| 12. | ALA4667676 | B | Inhibition of cathepsin D (unknown origin) at 10 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA4667677 | B | Inhibition of cathepsin E (unknown origin) at 10 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA4667678 | B | Inhibition of thrombin (unknown origin) at 10 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA4667679 | B | Inhibition of factor Xa (unknown origin) at 10 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 16. | ALA4667680 | B | Inhibition of cathepsin G (unknown origin) at 10 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 17. | ALA4667681 | B | Inhibition of KLK1 (unknown origin) at 10 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 18. | ALA4667682 | B | Inhibition of KLK2 (unknown origin) at 10 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 19. | ALA4667683 | B | Inhibition of tryptase (unknown origin) at 10 uM | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 20. | ALA4667684 | B | Inhibition of trypsin (unknown origin) at 10 uM | Homo sapiens | 3 | protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!