#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4670187	ADME	Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate incubated for 5 to 20 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	4	ALA4665778	microsome format	Scientific Literature
2.	ALA4670188	ADME	Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 5 to 20 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	4	ALA4665778	microsome format	Scientific Literature
3.	ALA4670189	ADME	Time-dependent inhibition of CYP3A4 in human liver microsomes assessed as activity loss using midazolam as substrate at 10 uM in presence of NADPH by LC-MS/MS analysis relative to control	Homo sapiens	4	ALA4665778	microsome format	Scientific Literature
4.	ALA4670190	ADME	Inhibition of recombinant N-terminal FLAG-tagged full-length human PI3K p110alpha/human p85alpha co- expressed in Sf9 insect cells using phosphatidylinositol 4,5-bisphosphate as substrate preincubated for 60 mins followed by substrate addition and measured after 1 hr in presence of ATP by ADP-Glo lipid kinase assay	Homo sapiens	39	ALA4665778	cell-based format	Scientific Literature
5.	ALA4670191	ADME	Inhibition of recombinant N-terminal FLAG-tagged full-length human PI3K p110beta/human p85alpha co- expressed in Sf9 insect cells using phosphatidylinositol 4,5-bisphosphate as substrate preincubated for 60 mins followed by substrate addition and measured after 1 hr in presence of ATP by ADP-Glo lipid kinase assay	Homo sapiens	39	ALA4665778	cell-based format	Scientific Literature
6.	ALA4670192	Binding	Inhibition of recombinant N-terminal His-tagged full-length human PI3K p120gamma expressed in Sf9 insect cells using phosphatidylinositol 4,5-bisphosphate as substrate preincubated for 60 mins followed by substrate addition and measured after 1 hr in presence of ATP by ADP-Glo lipid kinase assay	Homo sapiens	39	ALA4665778	cell-based format	Scientific Literature
7.	ALA4670193	ADME	Inhibition of recombinant N-terminal GST-tagged full-length human PI3K p110delta/p85alpha co- expressed in Sf9 insect cells using phosphatidylinositol 4,5-bisphosphate as substrate preincubated for 60 mins followed by substrate addition and measured after 1 hr in presence of ATP by ADP-Glo lipid kinase assay	Homo sapiens	39	ALA4665778	cell-based format	Scientific Literature
8.	ALA4670194	Binding	Inhibition of PI3Kgamma in human THP-1 cells assessed as reduction in Akt phosphorylation at S473 residue incubated for 60 mins by alphalisa assay	Homo sapiens	39	ALA4665778	cell-based format	Scientific Literature
9.	ALA4670195	ADME	Intrinsic clearance in human hepatocytes assessed per 10^6 cells at 0.5 uM by LC-MS/MS analysis	Homo sapiens	4	ALA4665778	cell-based format	Scientific Literature
10.	ALA4670196	ADME	Intrinsic clearance rat hepatocytes assessed per 10^6 cells by LC-MS/MS analysis	Rattus norvegicus	4	ALA4665778	tissue-based format	Scientific Literature
11.	ALA4670197	ADME	Clearance in Sprague-Dawley rat at 0.25 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	4	ALA4665778	organism-based format	Scientific Literature
12.	ALA4670198	ADME	Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 5 to 20 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	4	ALA4665778	microsome format	Scientific Literature
13.	ALA4670199	ADME	Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 5 to 20 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	4	ALA4665778	microsome format	Scientific Literature
14.	ALA4670200	ADME	Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 5 to 20 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	4	ALA4665778	microsome format	Scientific Literature
15.	ALA4670201	ADME	Volume of distribution at steady state in Sprague-Dawley rat at 0.25 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	4	ALA4665778	organism-based format	Scientific Literature
16.	ALA4670202	Binding	Selectivity index, ratio of IC50 for recombinant N-terminal FLAG-tagged full-length human PI3K p110alpha/human p85alpha to IC50 for recombinant N-terminal His-tagged full-length human PI3K p120gamma	Homo sapiens	38	ALA4665778	assay format	Scientific Literature
17.	ALA4670204	Binding	Selectivity index, ratio of IC50 for N-terminal GST-tagged full-length human PI3K p110delta/p85alpha to IC50 for recombinant N-terminal His-tagged full-length human PI3K p120gamma	Homo sapiens	38	ALA4665778	assay format	Scientific Literature