| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4705649 | B | Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract measured after 30 mins by fluorescence polarization assay | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 2. | ALA4705650 | B | Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 R106A/R109A mutant expressed in Escherichia coli S12 extract measured after 30 mins by fluorescence polarization assay | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 3. | ALA4705651 | B | Inhibition of FAM-Bim peptide binding to Bcl-xl (unknown origin) measured after 30 mins by fluorescence polarization assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA4705652 | B | Inhibition of FAM-Bim peptide binding to MCl1 (unknown origin) measured after 30 mins by fluorescence polarization assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA4705655 | F | Induction of apoptosis in human HL-60 cells measured after 48 hrs by FITC-Annexin V/PS staining based | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA4705656 | F | Induction of apoptosis in human OCI-AML-3 cells measured after 48 hrs by FITC-Annexin V/PS staining based | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4705657 | F | Induction of apoptosis in human KG-1 cells measured after 48 hrs by FITC-Annexin V/PS staining based | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4705658 | F | Induction of apoptosis in human MCF7 cells measured after 48 hrs by FITC-Annexin V/PS staining based | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA4705664 | B | Induction of BCl-2 dephosphorylation in human OCI-AML-3 cells at 5 to 10 uM measured after 24 hrs by coimmunoprecipitation method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4705666 | B | Induction of BCl-2 dephosphorylation in human OCI-AML-3 cells assessed as increase in Bax expression at 5 to 10 uM measured after 24 hrs by coimmunoprecipitation method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4705667 | B | Induction of BCl-2 dephosphorylation in human HL-60 cells at 5 to 10 uM measured after 24 hrs by coimmunoprecipitation method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4705668 | B | Induction of BCl-2 dephosphorylation in human HL-60 cells assessed as increase in Bax expression at 5 to 10 uM measured after 24 hrs by coimmunoprecipitation method | Homo sapiens | 2 | cell-based format | Scientific Literature |
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