# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4729856 | B | Inhibition of recombinant rat SK2 expressed in HEK293 cells at 10 nM and holding potential at 0 mV and ramp voltage from -100 to 100 mV by whole cell patch clamp method relative to control | Rattus norvegicus | 13 | ALA4725389 | cell-based format | Scientific Literature | |
2. | ALA4729857 | B | Inhibition of recombinant human SK3 expressed in HEK293T cells at 10 nM and holding potential at 0 mV and ramp voltage from -100 to 100 mV by whole cell patch clamp method relative to control | Homo sapiens | 13 | ALA4725389 | cell-based format | Scientific Literature | |
3. | ALA4729860 | B | Inhibition of recombinant human SK3 expressed in HEK293T cells assessed as ratio of amplitude of outward current blocked in presence and absence of compound at 1 nM and holding potential at 0 mV and ramp voltage from -100 to 100 mV by whole cell patch clamp method relative to control | Homo sapiens | 2 | ALA4725389 | cell-based format | Scientific Literature | |
4. | ALA4729861 | B | Inhibition of recombinant human SK3 expressed in HEK293T cells assessed as reduction in channel current with holding potential 0 mV and ramp voltage from -100 to 100 mV by whole cell patch clamp method | Homo sapiens | 3 | ALA4725389 | cell-based format | Scientific Literature | |
5. | ALA4729862 | F | Inhibition of cell migration in human MDA-MB-435 cells transfected with lentivrus-encoding shRNA against SK3 by matrigel invasion method relative to control | Homo sapiens | 3 | ALA4725389 | cell-based format | Scientific Literature | |
6. | ALA4729863 | B | Inhibition of SK3-dependent cell migration in human MDA-MB-435 cells assessed as ratio of total cells migrating by matrigel invasion method relative to control | Homo sapiens | 3 | ALA4725389 | cell-based format | Scientific Literature |