| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4703214 | F | Cytotoxicity against human MT2 cells infected with HTLV-1 assessed as reduction in metabolic activity at 50 uM incubated for 72 hrs in presence of resazurin by resazurin reduction method relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA4703216 | F | Cell cycle arrest in human MT2 cells infected with HTLV-1 assessed as accumulation at S phase at 50 uM incubated for 72 hrs by RNaseA/propidium iodide staining based FACSCalibur flow cytometry | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4703217 | F | Cell cycle arrest in human MT2 cells infected with HTLV-1 assessed as accumulation at G0/G1 phase at 50 uM incubated for 72 hrs by RNaseA/propidium iodide staining based FACSCalibur flow cytometry | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA4703218 | F | Cell cycle arrest in human MT2 cells infected with HTLV-1 assessed as accumulation at G2/M phase at 50 uM incubated for 72 hrs by RNaseA/propidium iodide staining based FACSCalibur flow cytometry | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA4703220 | F | Induction of apoptosis in human MT2 cells infected with HTLV-1 assessed as activation of caspase-3/7 at 50 uM measured after 72 hrs by CellEvent caspase 3/7 green detection reagent based assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA4703221 | F | Induction of apoptosis in human MT2 cells infected with HTLV-1 at 50 uM measured after 72 hrs by annexinV-Cy5/propidium iodide staining based FACSCalibur flow cytometry | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4703223 | F | Effect on HTLV-1 Tax expression in lentiviral pLVX-TET3G transduced human Jurkat LTR-GFP inducible Tax assessed as doxycyclin-treated GFP positive viable cells at 50 uM after 72 hrs by flow cytometry (Rvb = 16.82 +/- 3.37 %) | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 8. | ALA4703224 | A | Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability by measuring viability index at 50 uM after 72 hrs in presence of resazurin by resazurin reduction method | Homo sapiens | 5 | cell-based format | Scientific Literature |
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