| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4731217 | A | Inhibition of UGT2B17 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA4731218 | P | Thermodynamic solubility of the compound in DMSO at pH 7.4 | 7 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4731219 | B | Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 4. | ALA4731220 | B | Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 5. | ALA4731221 | A | Inhibition of UGT1A1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4731222 | A | Inhibition of UGT1A6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4731223 | A | Inhibition of UGT2B7 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4731224 | A | Inhibition of UGT2B15 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4731225 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 12 | microsome format | Scientific Literature | ||
| 10. | ALA4731226 | A | Apparent permeability of the compound at pH 6.5 to 7.4 by PAMPA | 12 | assay format | Scientific Literature | |||
| 11. | ALA4731227 | P | Distribution coefficient, log D of the compound | 14 | small-molecule physicochemical format | Scientific Literature | |||
| 12. | ALA4731228 | A | Drug uptake in C57BL/6 mouse brain at 3 mg/kg, iv measured at 5 mins | Mus musculus | 14 | organism-based format | Scientific Literature | ||
| 13. | ALA4731229 | A | Drug uptake in C57BL/6 mouse brain at 3 mg/kg, iv measured at 1 hr | Mus musculus | 14 | organism-based format | Scientific Literature | ||
| 14. | ALA4731230 | A | Ratio of drug concentration in brain to plasma in C57BL/6 mouse measured at 5 mins | Mus musculus | 14 | cell-free format | Scientific Literature | ||
| 15. | ALA4731231 | A | Ratio of drug concentration in brain to plasma in C57BL/6 mouse measured at 1 hr | Mus musculus | 14 | cell-free format | Scientific Literature | ||
| 16. | ALA4731232 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4731233 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4731234 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4731235 | A | AUC (0 to last) in Sprague-Dawley rat at 3 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4731236 | A | Cmax in Sprague-Dawley rat at 3 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!