# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4767142 | Functional | Adjuvanted-antitumor vaccine activity in C57BL/6 mouse bone marrow derived cells assessed as induction of IL-12 production at 10^-4 to 10^1 ug/ml incubated for 48 hrs by ELISA | Mus musculus | 5 | ALA4765240 | cell-based format | Scientific Literature | |
2. | ALA4767143 | Functional | Adjuvanted-antitumor vaccine activity in C57BL/6 mouse bone marrow derived cells assessed as induction of IL-6 production at 10^-4 to 10^1 ug/ml incubated for 48 hrs by ELISA | Mus musculus | 5 | ALA4765240 | cell-based format | Scientific Literature | |
3. | ALA4767149 | ADME | Cytotoxicity against OT2 mouse CD4-positive T cells xenografted in C57BL/6 mouse assessed as reduction in cell viability in splenocytes by flow cytometry analysis | Mus musculus | 3 | ALA4765240 | cell-based format | Scientific Literature | |
4. | ALA4767150 | Functional | Immuno-adjuvant activity in C57BL/6 mouse assessed as antibody response to Tn3G7K by measuring serum IgG levels at 11 .7 nmol, ID at day 0 and day 21 and measured post second dose | Mus musculus | 2 | ALA4765240 | organism-based format | Scientific Literature | |
5. | ALA4767155 | Functional | Adjuvanted-antitumor vaccine activity in C57BL/6 mouse assessed as induction of OT2-T cell mediated IFNgamma production in lymph node at 1 ug/ml, ID incubated for 5 days by anti-IFNgamma staining based flow cytometry | Mus musculus | 2 | ALA4765240 | organism-based format | Scientific Literature | |
6. | ALA4767156 | Functional | Immuno-adjuvant activity in C57BL/6 mouse assessed as antibody response to OVA peptide by measuring serum IgG levels at 11 .7 nmol, ID at day 0 and day 21 and measured post second dose | Mus musculus | 2 | ALA4765240 | organism-based format | Scientific Literature |