# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4729978 | B | Inhibition of human C-terminal His6-tagged CD73 expressed in CHO cells preincubated for 15 mins followed by AMP addition and measured after 10 mins by malachite green reagent based assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
2. | ALA4729979 | B | Inhibition of CD73 in human NCI-H1568 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and measured after 1 hr by LC-MS/MS analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
3. | ALA4729983 | B | Inhibition of CD73 in mouse EMT6 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and measured after 1 hr by LC-MS/MS analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
4. | ALA4729984 | A | AUC infinity in mouse at 200 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
5. | ALA4729985 | A | Cmax in mouse at 200 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
6. | ALA4729986 | A | Terminal half life in mouse at 200 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature |