# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4705080 | B | Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assay | Pseudomonas aeruginosa | 27 | single protein format | Scientific Literature | ||
2. | ALA4705081 | B | Displacement of fluorescent ligand from Escherichia coli LpxC measured after 30 mins by fluorescence anisotrophy assay | Escherichia coli | 27 | assay format | Scientific Literature | ||
3. | ALA4705082 | F | Antibacterial activity against Escherichia coli ATCC 25922 assessed as bacterial growth inhibition by CLSI based broth microdilution method | Escherichia coli | 27 | organism-based format | Scientific Literature | ||
4. | ALA4705091 | A | Protein binding in mouse plasma assessed as unbound fraction after 7 hrs by LC-MS/MS-based rapid equilibrium dialysis method | Mus musculus | 5 | cell-free format | Scientific Literature | ||
5. | ALA4705092 | A | Protein binding in rat plasma assessed as unbound fraction after 7 hrs by LC-MS/MS-based rapid equilibrium dialysis method | Rattus norvegicus | 5 | cell-free format | Scientific Literature | ||
6. | ALA4705095 | A | Inhibition of human AchE expressed in HEK293 cells using acetylthiocholine as substrate by Ellman's method | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA4705096 | A | Hemodynamic activity in Sprague-Dawley rat assessed as hypotension by measuring plasma drug concentration at 500 mg/kg/hr administered as iv infusion for 60 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature |