# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4670474 | F | Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 43 | ALA4665792 | cell-based format | Scientific Literature | |
2. | ALA4670475 | F | Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 43 | ALA4665792 | cell-based format | Scientific Literature | |
3. | ALA4670476 | F | Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 43 | ALA4665792 | cell-based format | Scientific Literature | |
4. | ALA4670477 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 43 | ALA4665792 | cell-based format | Scientific Literature | |
5. | ALA4670478 | A | Cytotoxicity against human L02 cells assessed as cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA4665792 | cell-based format | Scientific Literature | |
6. | ALA4670479 | A | Cytotoxicity against human HK2 cells assessed as cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA4665792 | cell-based format | Scientific Literature | |
7. | ALA4670481 | B | Inhibition of TrxR (unknown origin) in presence of NADPH by Ellman's method | Homo sapiens | 2 | ALA4665792 | assay format | Scientific Literature | |
8. | ALA4670482 | B | Inhibition of Escherichia coli Trx incubated for 1.5 hrs in presence of DTT and insulin | Escherichia coli | 2 | ALA4665792 | assay format | Scientific Literature | |
9. | ALA4670483 | B | Inhibition of TrxR in human HT-29 cells incubated for 30 mins in presence of insulin, NADPH and Trx by DTNB reagent based assay | Homo sapiens | 5 | ALA4665792 | cell-based format | Scientific Literature | |
10. | ALA4670484 | B | Inhibition of TrxR in human HT-29 cells incubated for 60 mins in presence of insulin, NADPH and Trx by DTNB reagent based assay | Homo sapiens | 5 | ALA4665792 | cell-based format | Scientific Literature | |
11. | ALA4670485 | B | Inhibition of TrxR in human HT-29 cells incubated for 90 mins in presence of insulin, NADPH and Trx by DTNB reagent based assay | Homo sapiens | 5 | ALA4665792 | cell-based format | Scientific Literature | |
12. | ALA4670486 | B | Covalent inhibition of TrxR (unknown origin) assessed as covalent bond formation incubated up to 30 mins in presence of NADPH by Ellman's method | Homo sapiens | 2 | ALA4665792 | assay format | Scientific Literature | |
13. | ALA4670487 | B | Covalent inhibition of TrxR (unknown origin) assessed as inactivation rate constant incubated up to 30 mins in presence of NADPH by Ellman's method | Homo sapiens | 2 | ALA4665792 | assay format | Scientific Literature | |
14. | ALA4670488 | B | Covalent inhibition of TrxR (unknown origin) assessed as ratio of Kinact to ki incubated up to 30 mins in presence of NADPH by Ellman's method | Homo sapiens | 2 | ALA4665792 | assay format | Scientific Literature | |
15. | ALA4670507 | B | Inhibition of TrxR in human HT-29 cells incubated for 24 hrs in presence of insulin, NADPH and Trx by DTNB reagent based assay | Homo sapiens | 2 | ALA4665792 | cell-based format | Scientific Literature | |
16. | ALA4670508 | B | Inhibition of Trx in human HT-29 cells incubated for 24 hrs in presence of insulin, NADPH and DTT | Homo sapiens | 2 | ALA4665792 | cell-based format | Scientific Literature | |
17. | ALA4670509 | B | Inhibition of GR in human HT-29 cells incubated for 24 hrs in presence of GSSG and NADPH | Homo sapiens | 2 | ALA4665792 | cell-based format | Scientific Literature | |
18. | ALA4670510 | B | Inhibition of GPx in human HT-29 cells incubated for 24 hrs in presence of GSH, NADPH and GR measured at 10 secs interval for 4 mins | Homo sapiens | 2 | ALA4665792 | cell-based format | Scientific Literature |