# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4688478 | Binding | Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Fluo-4 AM dye based fluorescence analysis | Homo sapiens | 22 | ALA4680310 | cell-based format | Scientific Literature | |
2. | ALA4688479 | ADME | Drug metabolism in human liver microsomes assessed as dansyl glutathione adduct formation at 100 microM incubated for 30 mins by HPLC/MS based fluorescence analysis relative to diclofenac dGSH adduct | Homo sapiens | 22 | ALA4680310 | microsome format | Scientific Literature | |
3. | ALA4688480 | ADME | Activation of human PXR ligand binding domain incubated for 1 hr by TR-FRET assay | Homo sapiens | 19 | ALA4680310 | single protein format | Scientific Literature |