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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4727043 | Physicochemical | Lipophilicity, logD of the compound at pH 7.4 by chromatographic method | 35 | ALA4725292 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA4727044 | Binding | Displacement of Alexa Fluor 647 labelled ligand from His6-thr-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant (unknown origin) after 30 mins by TR-FRET assay | Homo sapiens | 35 | ALA4725292 | single protein format | Scientific Literature | |
3. | ALA4727045 | Binding | Displacement of Alexa Fluor 647 labelled ligand from His6-tagged BRD4 BD2 (1 to 477 residues)/BD1 Y97A mutant (unknown origin) after 30 mins by TR-FRET assay | Homo sapiens | 35 | ALA4725292 | single protein format | Scientific Literature | |
4. | ALA4727046 | Binding | Inhibition of ATAD2 (unknown origin) by TR-FRET assay | Homo sapiens | 11 | ALA4725292 | single protein format | Scientific Literature | |
5. | ALA4727048 | Binding | Selectivity index, difference between pIC50 for His6-thr-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant (unknown origin) to pIC50 for His6-tagged BRD4 BD2 (1 to 477 residues)/BD1 Y97A mutant (unknown origin) | Homo sapiens | 34 | ALA4725292 | assay format | Scientific Literature | |
6. | ALA4727049 | ADME | Permeability of the compound in pH 7.4 phosphate buffer measured after 3 hrs by artificial membrane permeability assay based HPLC analysis | 5 | ALA4725292 | assay format | Scientific Literature |