| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4665920 | F | Positive allosteric modulator activity at human mGlu4 receptor/Gqi5 in presence of EC20 glutamate by calcium mobilization assay | Homo sapiens | 34 | assay format | Scientific Literature | ||
| 2. | ALA4665921 | F | Positive allosteric modulator activity at human mGlu4 receptor/Gqi5 assessed as maximum activity at 30 uM by calcium mobilization assay relative to glutamic acid | Homo sapiens | 29 | assay format | Scientific Literature | ||
| 3. | ALA4665922 | A | Protein binding in rat plasma assessed as unbound fraction | Rattus norvegicus | 4 | cell-free format | Scientific Literature | ||
| 4. | ALA4665923 | A | Protein binding in human plasma assessed as unbound fraction | Homo sapiens | 4 | cell-free format | Scientific Literature | ||
| 5. | ALA4665924 | A | Fraction unbound in rat brain homogenate | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
| 6. | ALA4665925 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 7. | ALA4665926 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 8. | ALA4665927 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 9. | ALA4665928 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 10. | ALA4665932 | A | Hepatic clearance in human | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 11. | ALA4665934 | A | Brain to plasma partition coefficient, Kp of the compound in Sprague-Dawley rat at 0.20 to 0.25 mg/kg, iv cassette dose measured at 0.25 hrs | Rattus norvegicus | 6 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!