# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4707539 | F | Antioxidant activity of compound assessed as trolox equivalent antioxidant capacity by ORAC-FL assay | 12 | ALA4706484 | assay format | Scientific Literature | ||
2. | ALA4707540 | B | Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's method | Rattus norvegicus | 14 | ALA4706484 | tissue-based format | Scientific Literature | |
3. | ALA4707541 | B | Inhibition of rat serum BChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's method | Rattus norvegicus | 14 | ALA4706484 | cell-free format | Scientific Literature | |
4. | ALA4707542 | B | Selectivity index, ratio of IC50 for rat serum butyrylcholinesterase to IC50 for rat cortex acetylcholinesterase | Rattus norvegicus | 13 | ALA4706484 | assay format | Scientific Literature | |
5. | ALA4707543 | B | Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's method | Homo sapiens | 14 | ALA4706484 | tissue-based format | Scientific Literature | |
6. | ALA4707544 | B | Inhibition of human serum BChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's method | Homo sapiens | 14 | ALA4706484 | cell-free format | Scientific Literature | |
7. | ALA4707545 | B | Selectivity index, ratio of IC50 for human serum BChe to IC50 for human erythrocytes AChE | Homo sapiens | 6 | ALA4706484 | assay format | Scientific Literature | |
8. | ALA4707557 | B | Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation at 25 uM by ThT fluorescence assay relative to control | Homo sapiens | 13 | ALA4706484 | single protein format | Scientific Literature | |
9. | ALA4707558 | B | Inhibition of human erythrocyte AChE-induced amyloid beta 1 to 40 (unknown origin) aggregation at 100 uM by thioflavin-T fluorescence method relative to control | Homo sapiens | 13 | ALA4706484 | tissue-based format | Scientific Literature | |
10. | ALA4707559 | B | Inhibition of copper-induced amyloid beta (1 to 42) (unknown origin) aggregation at 25 uM by ThT fluorescence assay relative to control | 13 | ALA4706484 | assay format | Scientific Literature | ||
11. | ALA4707560 | B | Disaggregation of self-induced amyloid beta (1 to 42) (unknown origin) preformed fibrils at 25 uM by ThT fluorescence assay relative to control | Homo sapiens | 13 | ALA4706484 | single protein format | Scientific Literature | |
12. | ALA4707561 | B | Disaggregation of Copper-induced amyloid beta (1 to 42) (unknown origin) preformed fibrils at 25 uM by ThT fluorescence assay relative to control | 13 | ALA4706484 | assay format | Scientific Literature | ||
13. | ALA4707562 | B | Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation at 25 uM measured after 24 hrs by TEM analysis | Homo sapiens | 2 | ALA4706484 | single protein format | Scientific Literature | |
14. | ALA4707563 | B | Disaggregation of self-induced amyloid beta (1 to 42) (unknown origin) preformed fibrils at 25 uM measured after 48 hrs by TEM analysis | Homo sapiens | 2 | ALA4706484 | single protein format | Scientific Literature | |
15. | ALA4707564 | A | Cytotoxicity against rat PC-12 cells assessed as reduction in cell viability <= 100 uM measured after 48 hrs by MTT assay | Rattus norvegicus | 2 | ALA4706484 | cell-based format | Scientific Literature | |
16. | ALA4707572 | B | Metal chelating activity assessed as Fe2+-compound complex formation at 37.5 uM in presence of 37.5 uM FeSO4 by UV-Vis spectrophotometric analysis | 2 | ALA4706484 | assay format | Scientific Literature | ||
17. | ALA4707573 | B | Metal chelating activity assessed as Zn2+-compound complex formation at 37.5 uM in presence of 37.5 uM ZnCl2 by UV-Vis spectrophotometric analysis | 2 | ALA4706484 | assay format | Scientific Literature | ||
18. | ALA4707574 | B | Metal chelating activity assessed as Cu2+-compound complex formation at 37.5 uM in presence of 37.5 uM CuCl2 by UV-Vis spectroscopic analysis | 1 | ALA4706484 | assay format | Scientific Literature | ||
19. | ALA4707575 | B | Metal chelating activity assessed as Al3+-compound complex formation at 37.5 uM in presence of 37.5 uM AlCl3 by UV-Vis spectrophotometric analysis | 1 | ALA4706484 | assay format | Scientific Literature | ||
20. | ALA4707579 | A | Cytotoxicity against human L02 cells assessed as cell viability at 6.25 uM measured after 72 hrs by MTT assay relative to control | Homo sapiens | 2 | ALA4706484 | cell-based format | Scientific Literature |