# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4688567 | B | Inhibition of recombinant human N-terminal His6-tagged GSK3beta H350L mutant expressed in baculovirus infected Sf21 cells using prephosphorylated polypeptide as substrate incubated for 1 min followed by substrate addition and measured after 30 mins by Kinase-Glo luminescence assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
2. | ALA4688568 | B | Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate incubated for 10 mins by Ellman's method | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
3. | ALA4688569 | B | Inhibition of human BChE using butyrylthiocholineiodide as substrate incubated for 10 mins by Ellman's method | Homo sapiens | 25 | single protein format | Scientific Literature | ||
4. | ALA4688570 | B | Inhibition of self-induced human amyloid beta (1 to 42) aggregation at 25 uM incubated for 24 hrs by thioflavin T-based fluorescence assay relative to control | Homo sapiens | 15 | single protein format | Scientific Literature | ||
5. | ALA4733695 | B | Protac activity at CRBN/GSK3beta in rat PC12 cells assessed as GSK3beta degradation by measuring GSK3beta protein level at 10 uM after 10 hrs by Western blotting analysis (Rvb = 95.3 to 100.6 %) | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
6. | ALA4733703 | B | Protac activity at CRBN/GSK3beta in rat PC12 cells assessed as GSK3beta degradation by measuring GSK3beta protein level at 20 uM after 10 hrs by Western blotting analysis (Rvb = 100 %) | Rattus norvegicus | 1 | cell-based format | Scientific Literature |